885069-29-4

Basic information

• Product Name: 2-(5-bromo-2-chlorophenyl)propan-2-ol
• Synonyms: 2-(5-bromo-2-chlorophenyl)propan-2-ol
• CAS NO: 885069-29-4
• Molecular Weight: 249.535
• Mol File: 885069-29-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(5-bromo-2-chlorophenyl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-bromo-2-chlorophenyl)propan-2-ol(885069-29-4)
• EPA Substance Registry System: 2-(5-bromo-2-chlorophenyl)propan-2-ol(885069-29-4)

Safety Data

• Hazardous Substances Data: 885069-29-4(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Odor

Slightly sweet

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemical products; building block in the production of other organic compounds

Toxicity

Low, not expected to cause harm to human health or the environment with proper safety precautions.

Upstream product

• 21739-92-4 5-bromo-2-chlorobenzoic acid 
• 676-58-4 methylmagnesium chloride 
• 76008-73-6 5-Bromo-2-chloro-benzoic acid ethyl ester 
• 251085-87-7 methyl 5-bromo-2-chloro-benzoate 
• 74-88-4 methyl iodide 
• 917-64-6 methyl magnesium iodide 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1318793-71-3 1-{4-chloro-3-[(dimethyl)(4-ethyloxyphenyl)methyl]phenyl}-1-deoxy-β-D-glucopyranose 
• 1318794-43-2 2,3,4,6-tetra-O-acetyl-1-deoxy-1-{4-chloro-3-[1-(4-ethoxyphenyl)-1-methylethyl]phenyl}-β-D-glucopyranose 
• 1318794-42-1 1-{4-chloro-3-[(dimethyl)(4-ethyloxyphenyl)methyl]phenyl}-1-deoxy-α/β-D-glucopyranose 
• 1318794-39-6 (5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)(dimethyl)methane 
• 1318794-41-0 1-{4-chloro-3-[(dimethyl)(4-ethyloxyphenyl)methyl]phenyl}-α/β-D-methyl glucopyranoside 
• 885069-30-7 2-[2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-2-ol 
• 1443151-77-6 2-{2-chloro-5-[4-( {2-[4-(fluoromethoxy)phenyl]ethyl}amino)-6-methoxy-1,3,5-triazin-2-yl]phenyl}propan-2-ol 
• 1443151-54-9 2-{2-chloro-5-[4-({2-[4-(difluoromethoxy)phenyl]ethyl}amino)-6-methoxy-1,3,5-triazin-2-yl]phenyl}propan-2-ol 
• 1443151-98-1 4-[2-({4-[4-Chloro-3-(1-hydroxy-1-methylethyl)phenyl]-6-methoxy-1,3,5-triazin-2-yl}amino)ethyl]phenol 
• 461432-25-7 (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 945717-56-6 4-bromo-1-chloro-2-(prop-1-en-2-yl)benzene 

Relevant articles and documents

STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI

The present invention relates to novel strobilurine type compounds, to compositions comprising at least one such compound, to methods for combating phytopathogenic fungi, to the use of such compounds and to seeds coated with at least one such compound.

PHENYL C-GLUCOSIDE DERIVATIVES, PREPARATION METHODS AND USES THEREOF

The present invention relates to a sodium glucose cotransporter 2 (SGLT2) inhibitor with a phenyl C-glucoside structure, its preparation method, a pharmaceutical composition containing the same, and its use in treating diabetes and preparing an anti-diabetes medicament. The invention provides a compound with the structure of general formula I and a pharmaceutically acceptable salt and prodrug ester thereof, wherein, the definitions of R5 and R6 are selected from the following: (1) R5=R6=Me; (2) R5=Me, R6=OMe; (3) R5=Me, R6=H; (4) R5=Me, R6=F; (5) R5=F, R6=H; and (6) R5=OMe, R6=H.

Gem-dimethyl-bearing C-glucosides as sodium-glucose co-transporter 2 (SGLT2) inhibitors

Three novel gem-dimethyl C-glucosides were designed as sodium-glucose co-transporter 2 (SGLT2) inhibitors, and their syntheses started from D-glucose and three 2-substituted-5-bromobenzoic acids were achieved via a facile 8-step protocol, with the key step being anhydrous aluminum chloride-catalyzed Friedel-Crafts alkylation of tertiary alcohols and phenetol. These three SGLT2 inhibitors were evaluated in vivo with a mice oral glucose tolerance test (OGTT), and the anti-hyperglycemic activities of all these three compounds were comparable with that of the positive control Dapagliflozin. Copyright