885268-47-3 Usage
General Description
Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate is a chemical compound that belongs to the class of spiro compounds. It has a molecular formula of C11H21N3O2 and a molecular weight of 223.30 g/mol. Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate is often used as a building block in the synthesis of various pharmaceutical drugs and organic compounds. It is a stable and non-reactive compound under normal conditions, making it suitable for use in chemical reactions and as a reagent in organic synthesis. Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate may also have potential applications in the field of medicinal chemistry and drug discovery due to its unique spiro structure and potential biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 885268-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,6 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 885268-47:
(8*8)+(7*8)+(6*5)+(5*2)+(4*6)+(3*8)+(2*4)+(1*7)=223
223 % 10 = 3
So 885268-47-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H22N2O2/c1-11(2,3)16-10(15)14-8-4-5-12(14)6-7-13-9-12/h13H,4-9H2,1-3H3
885268-47-3Relevant articles and documents
Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors
Sippy, Kevin B.,Anderson, David J.,Bunnelle, William H.,Hutchins, Charles W.,Schrimpf, Michael R.
scheme or table, p. 1682 - 1685 (2009/11/30)
Several N-pyridin-3-yl spirobicyclic diamines, designed as conformationally restricted analogs of tebanicline (ABT-594), were synthesized as novel ligands for nicotinic acetylcholine receptors (nAChR). The spirocyclic compounds exhibited weaker binding affinity, than other constrained analogs in accord with a pharmacophore model. Nevertheless, some (1a, 1b) possessed (partial) agonist potencies comparable to nicotine at the α4β2 subtype, but with greatly improved selectivity relative to the α3β4* nAChR.
