885270-83-7

Basic information

• Product Name: (2-AMINO-PHENYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (2-AMINO-PHENYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER;tert-butyl (2-aMinophenyl)(Methyl)carbaMate
• CAS NO: 885270-83-7
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28
• Mol File: 885270-83-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (2-AMINO-PHENYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-PHENYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER(885270-83-7)
• EPA Substance Registry System: (2-AMINO-PHENYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER(885270-83-7)

Safety Data

• Hazardous Substances Data: 885270-83-7(Hazardous Substances Data)

Usage

General Description

The chemical (2-amino-phenyl)-methyl-carbamic acid tert-butyl ester, also known as Boc-aniline, is a compound used in organic synthesis and pharmaceutical research. It is a tert-butyl ester derivative of aniline, which is a common building block in the synthesis of various pharmaceuticals and agrochemicals. Boc-aniline is known for its ability to act as a nucleophile in organic reactions, and it is often used as a protecting group for amine functionalities. (2-AMINO-PHENYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER is widely utilized in the production of a variety of pharmaceuticals, including anti-inflammatory drugs, antibiotics, and antiviral medications.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 4760-34-3 N-methyl-1,2-phenylenediamine 
• 54614-93-6 (2-nitro-phenyl)-carbamic acid tert-butyl ester 
• 88-74-4 2-nitro-aniline 
• 612-28-2 2-nitro-N-methylaniline 

Downstream Products

• 1037793-64-8 C₁₈H₂₁N₃O₆S 
• 1037793-72-8 C₁₄H₁₅N₃O₄S 
• 1037793-76-2 C₁₅H₁₄ClN₃O₅S 
• 1037793-68-2 C₁₉H₂₃N₃O₆S 
• 1037793-88-6 C₂₇H₃₈N₆O₆ 
• 1037793-92-2 C₂₈H₃₇ClN₆O₇ 
• 1037793-84-2 C₃₃H₄₁N₇O₁₀S 
• 1037793-99-9 C₅₄H₆₁ClN₈O₁₁ 

Relevant articles and documents

BENZOTHIADIAZINE COMPOUNDS

The invention is directed to substituted benzothiadiazine derivatives. Specifically, the invention is directed to compounds according to Formula (I):wherein R, R1, R2, R3, R4 and R5 are as defined herein. The compounds of the invention are inhibitors of CD73 and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with CD73 inhibition, such as AIDS, autoimmune diseases, infections, atherosclerosis, and ischemia-reperfusion injury. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting CD73 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.