885271-28-3

Basic information

• Product Name: 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE
• Synonyms: 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE
• CAS NO: 885271-28-3
• Molecular Formula: C₁₅H₁₂N₂O₂
• Molecular Weight: 252.27
• Mol File: 885271-28-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 485.896°C at 760 mmHg
• Flash Point: 247.661°C
• Appearance: /
• Density: 1.318g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.707
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE(885271-28-3)
• EPA Substance Registry System: 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE(885271-28-3)

Safety Data

• Hazardous Substances Data: 885271-28-3(Hazardous Substances Data)

Usage

General Description

5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE, also known as C23H18N2O2, is a chemical compound with the molecular formula C23H18N2O2. It is a white to off-white solid that is commonly used as a building block in organic synthesis and pharmaceutical research. 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE is a derivative of indazole, which is a bicyclic aromatic heterocycle. The presence of a benzyl ether and an aldehyde functional group in its structure makes it a versatile intermediate for the synthesis of various organic molecules. Additionally, 5-BENZYLOXY-1H-INDAZOLE-3-CARBALDEHYDE has been studied for its potential pharmacological activities, making it a valuable compound in drug discovery and development.

InChI:InChI=1/C15H12N2O2/c18-9-15-13-8-12(6-7-14(13)16-17-15)19-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)

Upstream product

• 1215-59-4 5-benzyloxy-1H-indole 

Downstream Products

• 485834-04-6 2-(5-(benzyloxy)-1H-indazol-3-yl)-6-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazole 

Relevant articles and documents

An optimized procedure for direct access to 1: H -indazole-3-carboxaldehyde derivatives by nitrosation of indoles

Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitrosation of indoles in a slightly acidic environment. These very mild conditions allow the conversion of both electron-rich and electron-deficient indoles into 1H-indazole-3-carboxaldehydes.