885275-80-9

Basic information

• Product Name: 1-BROMO-IMIDAZO[1,5-A]PYRIDINE
• Synonyms: 1-BROMO-IMIDAZO[1,5-A]PYRIDINE
• CAS NO: 885275-80-9
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.03
• Mol File: 885275-80-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.69±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.56±0.30(Predicted)
• CAS DataBase Reference: 1-BROMO-IMIDAZO[1,5-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-IMIDAZO[1,5-A]PYRIDINE(885275-80-9)
• EPA Substance Registry System: 1-BROMO-IMIDAZO[1,5-A]PYRIDINE(885275-80-9)

Safety Data

• Hazardous Substances Data: 885275-80-9(Hazardous Substances Data)

Usage

General Description

1-Bromo-imidazo[1,5-a]pyridine is a chemical compound with the formula C7H5BrN2. It is a heterocyclic organic compound that consists of a pyridine ring fused to an imidazole ring, with a bromine atom attached at the 1-position of the imidazole ring. 1-BROMO-IMIDAZO[1,5-A]PYRIDINE is often used as a building block in the synthesis of pharmaceuticals and other organic compounds. It is a versatile intermediate in organic chemistry and is used in the production of a wide range of products, including agrochemicals, dyes, and pharmaceuticals. 1-Bromo-imidazo[1,5-a]pyridine is known for its strong electrophilic reactivity, making it a valuable tool for the construction of complex organic molecules.

Upstream product

• 274-47-5 imidazo[1,5-a]pyridine 

Downstream Products

• 1379574-59-0 1-(phenylethynyl)-3-(p-tolylethynyl)imidazo[1,5-a]pyridine 
• 1379574-65-8 1,1'-bis(phenylethynyl)-3,3'-biimidazo[1,5-a]pyridinyl 
• 1379574-54-5 1-((4-methoxyphenyl)ethynyl)-3-(4-trifluoromethylphenylethynyl)imidazo[1,5-a]pyridine 
• 1379574-63-6 1,1'-bis(4-methoxyphenylethynyl)-3,3'-biimidazo[1,5-a]-pyridinyl 
• 1379574-56-7 3-(phenylethynyl)-1-(4-trifluoromethylphenylethynyl)-imidazo[1,5-a]pyridine 
• 1379574-64-7 1,1'-bis(4-trifluoromethylphenylethynyl)-3,3'-biimidazo-[1,5-a]pyridinyl 
• 1379574-58-9 1-(phenylethynyl)-3-(4-trifluoromethylphenylethynyl)-imidazo[1,5-a]pyridine 
• 1379574-55-6 1-(4-methoxyphenylethynyl)-3-(phenylethynyl)imidazo[1,5-a]pyridine 
• 1379574-57-8 3-(4-methoxyphenylethynyl)-1-(phenylethynyl)imidazo[1,5-a]-pyridine 
• 1379574-51-2 1-((4-trifluoromethylphenyl)ethynyl)imidazo[1,5-a]pyridine 
• 1379574-52-3 1-(phenylethynyl)imidazo[1,5-a]pyridine 
• 1379574-73-8 C₁₅H₉BrN₂ 
• 1379574-62-5 1-(4-N,N-dimetylphenylethynyl)-3-(4-trifluoromethylphenylethynyl)imidazo[1,5-a]pyridine 
• 151362-06-0 1,4-bis[4-(trifluoromethyl)phenyl]buta-1,3-diyne 

Relevant articles and documents

Palladium-catalyzed C-H bond direct alkynylation of 5-membered heteroarenes: A well-defined synthetic route to azole derivatives containing two different alkynyl groups

A widely applicable oxidative coupling of 5-membered heteroarenes and terminal alkynes that uses a combination of palladium and silver salts was developed. Under suitable conditions, imidazole and benzimidazole, which are sluggish under similar previously reported oxidative coupling conditions, as well as imidazo[1,5-a]pyridines, oxazole, benzoxazole, thiazole, and benzothiazole could be alkynylated. In addition, the bromine atom on the substrates was intact under the reaction conditions, and conventional Sonogashira coupling did not occur at all. With these reactivities in hand, a well-defined synthetic route to imidazo[1,5-a]pyridines and thiazole containing two different alkynyl groups was achieved in a simple manner. In addition, linear correlations were observed between the fluorescence wavelength and the Hammett substituent constants of aryl groups, not only on the C1- but also on the C3-alkynyl group of the obtained 1,3-bis(arylethynyl)imidazo [1,5-a]pyridines.