885277-59-8 Usage
Description
1-BOC-2,5-BIS-HYDROXYMETHYL-PYRROLIDINE is a versatile chemical compound that features a pyrrolidine ring with two hydroxymethyl groups and a BOC (tert-butoxycarbonyl) protecting group. This structure enables selective reactions with other functional groups and provides potential sites for further modification, making it a valuable reagent in organic synthesis and a key component in the production of pharmaceuticals and specialty chemicals.
Uses
Used in Organic Synthesis:
1-BOC-2,5-BIS-HYDROXYMETHYL-PYRROLIDINE is used as a reagent for the protection and deprotection of amino groups in peptide synthesis. The BOC protecting group allows for selective reactions with other functional groups, facilitating the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-BOC-2,5-BIS-HYDROXYMETHYL-PYRROLIDINE is utilized as a key intermediate in the synthesis of various drugs. Its versatile reactivity and functional groups contribute to the development of new medications with improved efficacy and reduced side effects.
Used in Specialty Chemicals:
1-BOC-2,5-BIS-HYDROXYMETHYL-PYRROLIDINE is also employed in the production of specialty chemicals, where its unique structure and reactivity are harnessed to create high-value compounds for specific applications, such as advanced materials and catalysts.
Check Digit Verification of cas no
The CAS Registry Mumber 885277-59-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 885277-59:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*7)+(2*5)+(1*9)=228
228 % 10 = 8
So 885277-59-8 is a valid CAS Registry Number.
885277-59-8Relevant articles and documents
Synthesis method of 2, 5-pyrrolidine dimethyl carbinol and derivatives thereof
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Paragraph 0078-0092, (2021/10/30)
The invention provides a synthetic method of 2, 5-pyrrolidine dimethyl carbinol and derivatives thereof, and belongs to the field of organic synthesis. The synthesis method of 2, 5-pyrrolidine dimethyl carbinol is characterized in that a reaction equation is shown in the specification; in the formula, PG1 is selected from any one of H, benzyl, carbobenzoxy, triphenylmethyl or p-methoxybenzyl, and Cat. is a hydrogenation catalyst. The method comprises the following reaction step that: step 1, a compound 1, the hydrogenation catalyst and H2 contact with one another to obtain a compound 2. According to the method, 2, 5-dicarboxaldehyde pyrrole is selected as a reaction starting raw material, and the specific hydrogenation catalyst is selected, so that the 2, 5-pyrrolidine dimethyl carbinol can be obtained in a one-step reduction and high-yield manner, and the production cost is effectively reduced.
An improved and scalable process for 3,8-diazabicyclo[3.2.1]octane analogues
Huang, Long Jiang,Teng, Da Wei
, p. 523 - 526 (2012/01/30)
An improved and scalable process for substituted 3,8-diazabicyclo[3.2.1] octane was developed. N-Benzyl-2,5-dicarbethoxy-pyrrolidine 2 was reduced to N-benzyl-2,5-dihydroxymethylpyrrolidine 9 and subsequently debenzylated to afford N-Boc-2,5-dihydroxymeth
