885463-77-4Relevant articles and documents
Unprecedented SnCl2-mediated cyclization of nitro arenes via N-N bond formation
Sawant, Devesh,Kumar, Rishi,Maulik, Prakas R.,Kundu, Bijoy
, p. 1525 - 1528 (2006)
A mild, efficient, one-pot protocol for the cyclization of nitro-aryl substrates using SnCl2 has been described. The mechanistic course of the reaction suggests the involvement of a hydroxylamine intermediate leading to an intramolecular cyclization via N-N bond formation. The versatility of the methodology has been demonstrated by using two nitro-aryl substrates derived from dihydroisoquinolines and dihydro-β-carbolines. The intramolecular cyclization led to the formation of indazoles in high yields and purities.