885520-70-7 Usage
Description
4-BROMO-6-FLUORO (1H)INDAZOLE is a halogenated indole derivative, a chemical compound characterized by the presence of a bromine and fluorine atom attached to a five-membered nitrogen-containing ring. 4-BROMO-6-FLUORO (1H)INDAZOLE is known for its potential role in the development of pharmaceuticals and has unique structural properties that make it a valuable intermediate in organic synthesis.
Used in Pharmaceutical Industry:
4-BROMO-6-FLUORO (1H)INDAZOLE is used as a key intermediate in the synthesis of PI3 kinase inhibitors for the development of targeted cancer therapies. PI3 kinases are enzymes that play a crucial role in cell growth, survival, and metabolism, and their dysregulation is often associated with various cancers. By inhibiting these enzymes, 4-BROMO-6-FLUORO (1H)INDAZOLE contributes to the design of drugs that can potentially treat cancer by targeting the molecular pathways involved in tumor growth and progression.
Check Digit Verification of cas no
The CAS Registry Mumber 885520-70-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,5,2 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 885520-70:
(8*8)+(7*8)+(6*5)+(5*5)+(4*2)+(3*0)+(2*7)+(1*0)=197
197 % 10 = 7
So 885520-70-7 is a valid CAS Registry Number.
885520-70-7Relevant articles and documents
QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR
-
Page/Page column 20, (2021/07/24)
The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
FURTHER SUBSTITUTED TRIAZOLO QUINOXALINE DERIVATIVES
-
Paragraph 0162-0164, (2020/02/08)
The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
ATR INHIBITOR AND APPLICATION THEREOF
-
Paragraph 0109; 0110, (2020/12/29)
Disclosed are a compound as an ATR inhibitor and an application in preparing a drug as an ATR inhibitor. In particular, disclosed is a compound represented by formula (I) or an isomer or pharmaceutically acceptable salt thereof.