885521-44-8 Usage
Description
4-FLUORO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER, also known as Methyl 4-Fluoro-1H-indazole-6-carboxylate, is an organic compound that serves as a key intermediate in the synthesis of various chemical compounds. It is characterized by the presence of a fluorine atom at the 4-position and a methyl ester group at the 6-position of the indazole ring, which contributes to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
4-FLUORO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER is used as a chemical intermediate for the preparation of N-Alkylated Indazoles and Indazoles. These compounds are known as ROR-gamma-T inhibitors, which play a crucial role in the development of potential therapeutic agents for various diseases and disorders.
In the pharmaceutical industry, 4-FLUORO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER is utilized in the synthesis of ROR-gamma-T inhibitors, which are a class of compounds that target the ROR-gamma-t isoform of the retinoic acid-related orphan receptors (RORs). These receptors are involved in various biological processes, including immune response, circadian rhythm regulation, and cell differentiation. By inhibiting ROR-gamma-T, these compounds can potentially modulate these processes and offer therapeutic benefits in treating autoimmune diseases, inflammatory disorders, and other conditions.
Furthermore, the unique chemical structure of 4-FLUORO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER allows for the development of novel and more potent ROR-gamma-T inhibitors with improved pharmacological properties. This can lead to the discovery of new drugs with better efficacy, safety, and selectivity, ultimately benefiting patients and advancing the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 885521-44-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,5,2 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 885521-44:
(8*8)+(7*8)+(6*5)+(5*5)+(4*2)+(3*1)+(2*4)+(1*4)=198
198 % 10 = 8
So 885521-44-8 is a valid CAS Registry Number.
885521-44-8Relevant articles and documents
N-ALKYLATED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
-
Paragraph 0264, (2015/08/04)
The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts or solvates thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.
