885679-09-4

Basic information

• Product Name: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(3,4-difluorobenzyl)pent-4-enamide
• Synonyms: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(3,4-difluorobenzyl)pent-4-enamide
• CAS NO: 885679-09-4
• Molecular Weight: 444.887
• Mol File: 885679-09-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(3,4-difluorobenzyl)pent-4-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(3,4-difluorobenzyl)pent-4-enamide(885679-09-4)
• EPA Substance Registry System: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(3,4-difluorobenzyl)pent-4-enamide(885679-09-4)

Safety Data

• Hazardous Substances Data: 885679-09-4(Hazardous Substances Data)

Upstream product

• 22952-32-5 5-chloro-2-methoxybenzenesulfonyl chloride 
• 885679-07-2 2-([(5-chloro-2-methoxyphenyl)sulfonyl]amino)pent-4-enoic acid 
• 72235-53-1 3,4-difluorobenzylamine 
• 1069-48-3 rac-allylglycine 

Downstream Products

• 913563-92-5 2-{N-[(5-chloro-2-methoxyphenyl)sulfonyl]-N-(2-trifluoromethylallyl)amino}-N-(3,4-diifluorobenzyl)pent-4-enamide 
• 885679-12-9 2-[(5-chloro-2-methoxyphenylsulfonyl)(2-fluoroallyl)amino]-N-(3,4-difluorobenzyl)-4-pentenamide 

Relevant articles and documents

RCM-mediated synthesis of trifluoromethyl-containing nitrogen heterocycles

(Chemical Equation Presented) A ring-closing metathesis mediated pathway to trifluoromethyl-containing piperidines is detailed. This involves the development of a synthetic route to a new (trifluoromethyl)allylating reagent via a Diels-Alder/retro-Diels-Alder strategy, its application in the synthesis of a series of trifluormethyl-substituted diolefin recursors for ring-closing metathesis, and eventually the successful cyclization of these precursor molecules into the corresponding functionalized piperidines.