88578-92-1

Basic information

• Product Name: 2-CHLORO-4-FLUOROBENZOTRICHLORIDE
• Synonyms: 2-CHLORO-4-FLUOROBENZOTRICHLORIDE;2-Chloro-4-fluorobenzotrichoride
• CAS NO: 88578-92-1
• Molecular Formula: C₇H₃Cl₄F
• Molecular Weight: 247.91
• Mol File: 88578-92-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 256.9 °C at 760 mmHg
• Flash Point: 121.9 °C
• Appearance: /
• Density: 1.579 g/cm³
• Vapor Pressure: 0.0241mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 2-CHLORO-4-FLUOROBENZOTRICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-FLUOROBENZOTRICHLORIDE(88578-92-1)
• EPA Substance Registry System: 2-CHLORO-4-FLUOROBENZOTRICHLORIDE(88578-92-1)

Safety Data

• Hazardous Substances Data: 88578-92-1(Hazardous Substances Data)

Usage

General Description

2-CHLORO-4-FLUOROBENZOTRICHLORIDE is a chemical compound with the molecular formula C6H2Cl4F. It is a chlorinated aromatic compound that is used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a precursor in the production of various specialty chemicals and materials. 2-CHLORO-4-FLUOROBENZOTRICHLORIDE is a white crystalline solid that is insoluble in water but soluble in organic solvents. It is considered to be a hazardous chemical due to its toxic and irritant properties and should be handled with care in a controlled environment.

InChI:InChI=1/C7H3Cl4F/c8-6-3-4(12)1-2-5(6)7(9,10)11/h1-3H

Upstream product

• 452-64-2 3,4-dimethyl-fluorobenzene 

Downstream Products

• 908009-54-1 2-chloro-4-fluoro-5-nitro-benzotrichloride 
• 890933-20-7 2-chlorodifluoromethyl-4-fluorobenzal chloride 
• 858672-66-9 2-trifluoromethyl-4-fluorobenzal chloride 
• 890933-21-8 2-dichlorofluoromethyl-4-fluorobenzal chloride 
• 890933-18-3 2-chlorofluoromethyl-5-fluorobenzotrifluoride 
• 852462-70-5 2-trifluoromethyl-5-fluorobenzal chloride 
• 890933-19-4 2-chlorodifluoromethyl-5-fluorobenzal chloride 
• 90381-02-5 2-chlorofluoromethyl-4-fluorobenzotrifluoride 

Relevant articles and documents

FLUORINE-CONTAINING BENZAL CHLORIDE AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide 2-trifluoromethyl-5-fluorobenzal chloride and 2-trifluoromethyl-4-fluorobenzal chloride useful as a medicinal or an agrochemical intermediate, etc., and a method for producing them. SOLUTION: The 2-trifluoromethyl-5-fluorobenzal chloride is obtained by chlorinating 3,4-dimethylfluorobenzene with chlorine (Cl2) to obtain an isomer mixture (chlorination reaction mixture) of 2-trichloromethyl-5-fluorobenzal chloride and 2-trichloromethyl-4-fluorobenzal chloride, bringing the obtained isomer mixture in contact with hydrogen fluoride (HF) to obtain the fluorination reaction mixture, distilling the fluorination reaction mixture to be able to isolate 2-trifluoromethyl-5-fluorobenzal chloride. On the one hand, by reacting the distillation residue with HF under a condition for accelerating the reaction or for a longer period, 2-trifluoromethyl-4-fluorobenzal chloride is obtained.