886366-13-8 Usage
Description
1-(4-Trifluoromethyl-phenyl)-cyclopropanecarboxylic acid is a cyclopropane derivative that belongs to the class of carboxylic acids. It contains a trifluoromethyl group and a phenyl group, making it a versatile chemical building block with potential applications in various fields.
Uses
Used in Medicinal Chemistry and Drug Discovery:
1-(4-Trifluoromethyl-phenyl)-cyclopropanecarboxylic acid is used as a building block for the synthesis of new pharmaceuticals. Its unique physicochemical properties, imparted by the trifluoromethyl group, make it useful in the development of novel materials and chemical technologies.
Used in Pharmaceutical Development:
1-(4-Trifluoromethyl-phenyl)-cyclopropanecarboxylic acid is used as a structural constraint and conformational rigidity provider in drug design. This can enhance the potency and selectivity of bioactive compounds, making it beneficial for the development of new drugs.
Used in Materials Science:
1-(4-Trifluoromethyl-phenyl)-cyclopropanecarboxylic acid is used in the development of novel materials due to its unique properties conferred by the trifluoromethyl group. This makes it a valuable component in creating advanced materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 886366-13-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,3,6 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 886366-13:
(8*8)+(7*8)+(6*6)+(5*3)+(4*6)+(3*6)+(2*1)+(1*3)=218
218 % 10 = 8
So 886366-13-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H9F3O2/c12-11(13,14)8-3-1-7(2-4-8)10(5-6-10)9(15)16/h1-4H,5-6H2,(H,15,16)
886366-13-8Relevant articles and documents
USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS
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, (2022/02/19)
A medicament for treating or preventing pruritus is provided. For the medicament for treating or preventing pruritus, a compound having a blocking action on Cav3.2T-type calcium channels represented by General Formulas (I) to (VI), a tautomer of the compo
CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES
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Page/Page column 119, (2021/07/02)
The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: (I) wherein, RA1, RA2, RC and RD are as defined herein.
Pd(II)-Catalyzed Enantioselective C(sp3)-H Arylation of Free Carboxylic Acids
Shen, Peng-Xiang,Hu, Liang,Shao, Qian,Hong, Kai,Yu, Jin-Quan
, p. 6545 - 6549 (2018/05/23)
A monoprotected aminoethyl amine chiral ligand based on an ethylenediamine backbone was developed to achieve Pd-catalyzed enantioselective C(sp3)-H arylation of cyclopropanecarboxylic and 2-aminoisobutyric acids without using exogenous directing groups. This new chiral catalyst affords new disconnection for preparing diverse chiral carboxylic acids from simple starting materials that are complementary to the various ring forming approaches.
