88637-00-7

Basic information

• Product Name: 2-(Benzylamino)-6-methylpyrimidin-4-ol
• Synonyms: 2-(Benzylamino)-6-methylpyrimidin-4-ol;2-(benzylamino)-6-methylpyrimidin-4(3H)-one
• CAS NO: 88637-00-7
• Molecular Formula: C₁₂H₁₃N₃O
• Molecular Weight: 215.26
• Mol File: 88637-00-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: >250 °C
• Boiling Point: 361.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• PKA: 9.91±0.50(Predicted)
• CAS DataBase Reference: 2-(Benzylamino)-6-methylpyrimidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Benzylamino)-6-methylpyrimidin-4-ol(88637-00-7)
• EPA Substance Registry System: 2-(Benzylamino)-6-methylpyrimidin-4-ol(88637-00-7)

Safety Data

• Hazardous Substances Data: 88637-00-7(Hazardous Substances Data)

Usage

Structure

Pyrimidine derivative with a benzylamino group at position 2 and a methyl group at position 6

Biological activities

Potential pharmaceutical applications, possible therapeutic properties

Need for further research

To fully understand its potential uses and effects

Upstream product

• 53736-37-1 2-nitroamino-4(3H)-pyrimidinone 
• 100-46-9 benzylamine 
• 56-04-2 6-methyl-2-thiouracil 
• 6328-58-1 6-methyl-2-methylsulfanyl-3H-pyrimidin-4-one 
• 55-67-4 benzyl-guanidine; hydrobromide 
• 141-97-9 ethyl acetoacetate 
• 2551-73-7 1-benzylguanidine hemisulfate 
• 2211-57-6 N-benzylguanidine 

Downstream Products

• 25710-11-6 benzyl-(4-chloro-6-methylpyrimidin-2-yl)amine 

Relevant articles and documents

Preparation method of 2-alkyl amine pyrimidone

The invention discloses a preparation method of 2-alkyl amine pyrimidine. The preparation method comprises steps as follows: available 2-hydrocarbyl thiopyrimidone is taken as a raw material, and is oxidized into 2-sulfonyl pyrimidine by an oxidizing agen

Synthesis and antimicobacterial activity of 2-substituted 4-arylamino-6-methylpyrimidines

2-Substituted 4-arylamino-6-methylpyrimidines were synthesized by stepwise modification of the structure of 6-methyl-2-thiouracyl through the intermediate 2-(ar)alkylthio-6-methyl-4-chloropyrimidines. Some of the compounds synthesized exhibit expressed antimycobacterial activity.