886371-77-3 Usage
General Description
5-BROMO-2-TRIFLUOROMETHOXY-PYRIDINE is a chemical compound with the molecular formula C6H3BrF3NO. It is a pyridine derivative containing a bromine atom and three trifluoromethoxy groups. 5-BROMO-2-TRIFLUOROMETHOXY-PYRIDINE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is known for its reactivity and versatility, making it a valuable reagent in organic synthesis. Additionally, its unique structure and properties make it an important intermediate in the development of new materials and functional molecules. As a result, 5-BROMO-2-TRIFLUOROMETHOXY-PYRIDINE is widely used in the chemical industry and research laboratories for a variety of applications.
Check Digit Verification of cas no
The CAS Registry Mumber 886371-77-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,3,7 and 1 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 886371-77:
(8*8)+(7*8)+(6*6)+(5*3)+(4*7)+(3*1)+(2*7)+(1*7)=223
223 % 10 = 3
So 886371-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H3BrF3NO/c7-4-1-2-5(11-3-4)12-6(8,9)10/h1-3H
886371-77-3Relevant articles and documents
Regioselective Synthesis of N-Heteroaromatic Trifluoromethoxy Compounds by Direct O-CF3 Bond Formation
Liang, Apeng,Han, Shuaijun,Liu, Zhenwei,Wang, Liang,Li, Jingya,Zou, Dapeng,Wu, Yangjie,Wu, Yusheng
, p. 5102 - 5106 (2016)
The first one-step method for the synthesis of ortho-N-heteroaromatic trifluoromethoxy derivatives by site-specific O-CF3 bond formation using hydroxylated N-heterocycles and Togni's reagent is described. The approach enables the unprecedented syntheses of a wide range of six or five-membered N-heteroaromatic trifluoromethoxy compounds containing one or two heteroatoms from most commonly used hydroxylated N-heterocycles. Notable advantages of this method include its simplicity and mild conditions, avoidance of the need for metals or toxic reagents, and compatibility with a variety of functional groups. Furthermore, this method is especially suitable for the larger scale application.
