886498-84-6 Usage
General Description
2',6'-Difluoro-4'-Methoxyacetophenone is a chemical compound that falls into the category of aromatic ketones, which are utilized widely in organic chemistry. This specific compound is characterized by the presence of two fluorine atoms and a methoxy group attached to a central acetophenone group. The fluorine atoms contribute to its unique properties, such as high electronegativity and small atomic size. 2',6'-DIFLUORO-4'-METHOXYACETOPHENONE is often used in the development of other complex organic compounds, primarily in research and development settings. Its physical and chemical properties like melting point, boiling point, and solubility often vary depending upon the conditions under which they are observed.
Check Digit Verification of cas no
The CAS Registry Mumber 886498-84-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,4,9 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 886498-84:
(8*8)+(7*8)+(6*6)+(5*4)+(4*9)+(3*8)+(2*8)+(1*4)=256
256 % 10 = 6
So 886498-84-6 is a valid CAS Registry Number.
886498-84-6Relevant articles and documents
Pd-Catalysed direct C(sp2)-H fluorination of aromatic ketones: Concise access to anacetrapib
Wu, Qiuzi,Mao, Yang-Jie,Zhou, Kun,Wang, Shuang,Chen, Lei,Xu, Zhen-Yuan,Lou, Shao-Jie,Xu, Dan-Qian
supporting information, p. 4544 - 4547 (2021/05/17)
The Pd-cataylsed direct ortho-C(sp2)-H fluorination of aromatic ketones has been developed for the first time. The reaction features good regioselectivity and simple operations, constituting an alternative shortcut to access fluorinated ketones. A concise synthesis of anacetrapib has also been achieved by using late-stage C-H fluorination as a key step.
Modulators Of HEC1 Activity And Methods Therefor
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Page/Page column 21, (2011/10/10)
Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Especially preferred compounds disrupt Nek2/Hec1 binding and are therefore useful as chemotherapeutic agent for neoplastic diseases.
