886503-08-8 Usage
Description
2,6-DICHLORO-4-(TRIFLUOROMETHOXY)BENZYL BROMIDE, also known as 2-(Bromomethyl)-1,3-dichloro-5-(trifluoromethoxy)benzene, is an organic compound characterized by its unique molecular structure featuring a benzene ring with two chlorine atoms at the 2nd and 6th positions, a trifluoromethoxy group at the 4th position, and a bromomethyl group. 2,6-DICHLORO-4-(TRIFLUOROMETHOXY)BENZYL BROMIDE is known for its reactivity and potential applications in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
2,6-DICHLORO-4-(TRIFLUOROMETHOXY)BENZYL BROMIDE is used as a reactant in the preparation of benzylindazole derivatives, which serve as Bub1 kinase inhibitors. These inhibitors are of significant interest in the development of targeted therapies for cancer treatment, as they can help regulate cell cycle progression and mitotic spindle formation, thereby preventing the proliferation of cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 886503-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,5,0 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 886503-08:
(8*8)+(7*8)+(6*6)+(5*5)+(4*0)+(3*3)+(2*0)+(1*8)=198
198 % 10 = 8
So 886503-08-8 is a valid CAS Registry Number.
886503-08-8Relevant articles and documents
COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION
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, (2022/03/09)
The present disclosure relates generally to compounds and pharmaceutical compositions for the selective inhibition of histone lysine demethylase5 (KDM5), particularly KDM5B, and methods of their use in treating conditions and diseases associated with KDM5 activity.
