886792-81-0Relevant articles and documents
Efficient synthesis of N-arylpiperazinones via a selective intramolecular Mitsunobu cyclodehydration
Weissman, Steven A.,Lewis, Stephanie,Askin, David,Volante,Reider, Paul J.
, p. 7459 - 7462 (1998)
A practical two pot synthesis of N-arylpiperazinones from the corresponding aniline is described. The key transformation is a selective intramolecular Mitsunobu cyclodehydration of an amidoalcohol intermediate. A series of N-arylpiperazinones were prepared in yields up to 89%.
Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2
Shin, Young Sup,Lee, Jun Young,Noh, Soojin,Kwak, Yoonna,Jeon, Sangeun,Kwon, Sunoh,Jin, Young-hee,Jang, Min Seong,Kim, Seungtaek,Song, Jong Hwan,Kim, Hyoung Rae,Park, Chul Min
supporting information, (2020/11/13)
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) continues to spread worldwide, with 25 million confirmed cases and 800 thousand deaths. Effective treatments to target SARS-CoV-2 are urgently needed. In the present study, we have identified a
