887338-43-4

Basic information

• Product Name: 3-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1H-indole
• Synonyms: 3-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1H-indole
• CAS NO: 887338-43-4
• Molecular Weight: 639.791
• Mol File: 887338-43-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1H-indole(887338-43-4)
• EPA Substance Registry System: 3-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1H-indole(887338-43-4)

Safety Data

• Hazardous Substances Data: 887338-43-4(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 38184-10-0 phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 31271-90-6 1-(p-toluenesulfonyl)-1H-indole 
• 887339-08-4 1-tosyl-3-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)-1H-indole 
• 90481-77-9 3-bromo-1-(4-methylbenzenesulfonyl)-1H-indole 

Downstream Products

• 1352714-46-5 C₄₆H₄₇NO₇ 
• 1352714-47-6 2-(3-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)-1H-indol-1-yl)acetic acid 

Relevant articles and documents

Dehydrative glycosylation with cyclic phosphonium anhydrides

Cyclic phosphonium anhydrides generated from bis-phosphine oxides and trifluoromethanesulfonic anhydride are shown as general coupling reagents in a dehydrative glycosylation reaction of C1-hemiacetals. This reaction protocol is characterized by a broad substrate scope and high yields, including reactions of O-, C-, N-, and S-based nucleophiles with furanose, pyranose, and deoxysugar donors.

THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.