88745-26-0

Basic information

• Product Name: 1(2H)-Naphthalenone, 3,4-dihydro-3-methyl-, (R)-
• CAS NO: 88745-26-0
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 88745-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(2H)-Naphthalenone, 3,4-dihydro-3-methyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Naphthalenone, 3,4-dihydro-3-methyl-, (R)-(88745-26-0)
• EPA Substance Registry System: 1(2H)-Naphthalenone, 3,4-dihydro-3-methyl-, (R)-(88745-26-0)

Safety Data

• Hazardous Substances Data: 88745-26-0(Hazardous Substances Data)

Upstream product

• 660820-44-0 2-(2-methylallyl)benzaldehyde 

Relevant articles and documents

Rhodium-Catalyzed, Enantioselective Hydroacylation of ortho-Allylbenzaldehydes

The development of a rhodium catalyst for endo- and enantioselective hydroacylation of ortho-allylbenzaldehydes is reported. A catalyst generated in situ from [Rh(COD)Cl]2, (R)-DTBM-SEGPHOS, and NaBARF promotes the desired hydroacylation reactions and minimizes the formation of byproducts from competitive alkene isomerization and ene/dehydration pathways. These rhodium-catalyzed processes generate the 3,4-dihydronaphthalen-1(2H)-one products in moderate-to-high yields (49-91%) with excellent enantioselectivities (96-99% ee).