887588-20-7 Usage
Description
2-BROMOMETHYL-5NITROPYRIDINE, with the molecular formula C6H5BrN2O2, is a yellow crystalline solid that serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. As a pyridine derivative, it features a nitro group and a bromomethyl group, making it a valuable building block in organic synthesis for creating compounds with biological or industrial applications. Its potential extends to materials science and as a reagent in chemical research.
Uses
Used in Pharmaceutical Industry:
2-BROMOMETHYL-5NITROPYRIDINE is used as a key intermediate for the synthesis of various pharmaceutical compounds, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2-BROMOMETHYL-5NITROPYRIDINE is utilized as an intermediate in the production of agrochemicals, playing a crucial role in the development of pesticides and other agricultural chemicals to enhance crop protection and yield.
Used in Organic Synthesis:
2-BROMOMETHYL-5NITROPYRIDINE is used as a building block in organic synthesis for the creation of a wide range of biologically active and industrially relevant compounds, showcasing its versatility in chemical reactions.
Used in Materials Science:
2-BROMOMETHYL-5NITROPYRIDINE has potential applications in the field of materials science, where it can be employed to develop new materials with specific properties for various uses.
Used as a Research Reagent:
2-BROMOMETHYL-5NITROPYRIDINE is used as a reagent in chemical research, facilitating the exploration of new chemical reactions and the discovery of novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 887588-20-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,8 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 887588-20:
(8*8)+(7*8)+(6*7)+(5*5)+(4*8)+(3*8)+(2*2)+(1*0)=247
247 % 10 = 7
So 887588-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H5BrN2O2/c7-3-5-1-2-6(4-8-5)9(10)11/h1-2,4H,3H2
887588-20-7Relevant articles and documents
Selective Inhibitors of G2019S-LRRK2 Kinase Activity
Garofalo, Albert W.,Bright, Jessica,De Lombaert, Stéphane,Toda, Alyssa M. A.,Zobel, Kerry,Andreotti, Daniele,Beato, Claudia,Bernardi, Silvia,Budassi, Federica,Caberlotto, Laura,Gao, Peng,Griffante, Cristiana,Liu, Xinying,Mengatto, Luisa,Migliore, Marco,Sabbatini, Fabio Maria,Sava, Anna,Serra, Elena,Vincetti, Paolo,Zhang, Mingliang,Carlisle, Holly J.
, p. 14821 - 14839 (2020/11/30)
Pathogenic variants in the leucine-rich repeat kinase 2 (LRRK2) gene have been identified that increase the risk for developing Parkinson's disease in a dominantly inherited fashion. These pathogenic variants, of which G2019S is the most common, cause abnormally high kinase activity, and compounds that inhibit this activity are being pursued as potentially disease-modifying therapeutics. Because LRRK2 regulates important cellular processes, developing inhibitors that can selectively target the pathogenic variant while sparing normal LRRK2 activity could offer potential advantages in heterozygous carriers. We conducted a high-throughput screen and identified a single selective compound that preferentially inhibited G2019S-LRRK2. Optimization of this scaffold led to a series of novel, potent, and highly selective G2019S-LRRK2 inhibitors.
Thiophene compound Tetrahydrobenza and (by machine translation)
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Paragraph 0383; 0384, (2016/10/09)
The purpose of this invention is to provide with intestinal phosphate transport protein inhibit function (NPT-IIb), hyperphosphatemia as a therapeutic and/or preventive agent for Tetrahydrobenza the effective ingredient of benzothiophene compound or its stereoisomers, geometric isomers, tautomers, nitrogen oxide, hydrate, solvate, metabolite, ester, pharmaceutically acceptable salt or its prodrug and pharmaceutical composition. (by machine translation)
