88775-24-0

Basic information

• Product Name: 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)butyronitrile
• CAS NO: 88775-24-0
• Molecular Weight: 369.374
• Mol File: 88775-24-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)butyronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)butyronitrile(88775-24-0)
• EPA Substance Registry System: 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)butyronitrile(88775-24-0)

Safety Data

• Hazardous Substances Data: 88775-24-0(Hazardous Substances Data)

Upstream product

• 88775-47-7 (2E)-1-(2H-benzo[3,4-d]1,3-dioxolan-5-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 
• 151-50-8 potassium cyanide 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 6329-73-3 1-benzo[1,3]dioxol-5-yl-ethanol 
• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 
• 120-57-0 piperonal 

Downstream Products

• 88775-66-0 6,7-methylenedioxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydronaphthalen-1(2H)-one 
• 88775-50-2 methyl 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)-butyrate 
• 88775-32-0 4-(3,4-methylenedioxyphenyl)-2-(3,4,5-trimethoxyphenyl)butyric acid 
• 158979-65-8 (E)-2-(3,4,5-trimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxo-2-butenoic acid 
• 158979-69-2 1,t-2-bis(3,4,5-trimethoxyphenyl)-c-2,t-4-bis(3,4-methylenedioxybenzoyl)-r-1,t-3-cyclobutanedicarboxylic acid 
• 88775-51-3 methyl (Z)-2-(3,4,5-trimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxo-2-butenoic acid 
• 88775-49-9 (Z)-2-(3,4,5-trimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxo-2-butenoic acid 
• 138037-37-3 (Z)-2-(3,4,5-trimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxo-2-butenonitrile 
• 138037-36-2 (E)-2-(3,4,5-trimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxo-2-butenonitrile 
• 138037-38-4 1,t-2-bis(3,4,5-trimethoxyphenyl)-c-3,t-4-bis(3,4-methylenedioxybenzoyl)-r-1,c-2-cyclobutanedinitrile 
• 138037-38-4 1,t-2-bis(3,4,5-trimethoxyphenyl)-c-3,c-4-bis(3,4-methylenedioxybenzoyl)-r-1,c-2-cyclobutanedinitrile 
• 88775-41-1 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)butyramide 
• 88775-29-5 4-(3,4-methylenedioxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)butyric acid 

Relevant articles and documents

Studies on the chemical constituents of rutaceous plants. XLIX. Development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (1). Preparation of various 2,4-bisaryl-4-oxobutyronitriles and 2,4-bisaryl-4-oxobutyramides

For the sake of establishment of a versatile synthetic method for benzo[c]phenanthridine alkaloids, improvement of the Robinson synthetic method was examined. Thirteen chalcones (7a-m) were prepared by condensation of two acetophenone derivatives (15 and 16) with eleven benzaldehyde derivatives (19a-k) as fundamental starting materials. Hydrocyanation of these chalcones (7a-1) except one (7m) gave the corresponding 2,4-bisaryl-4-oxobutyronitriles (8a-1). Eleven 2,4-bisaryl-4-oxobutyramides (9a-k) were also prepared.