88796-02-5

Basic information

• Product Name: 4-Piperidinecarboxaldehyde, 1-(phenylmethyl)-, oxime
• CAS NO: 88796-02-5
• Molecular Formula: C13H18N2O
• Molecular Weight: 218.299
• Mol File: 88796-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarboxaldehyde, 1-(phenylmethyl)-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarboxaldehyde, 1-(phenylmethyl)-, oxime(88796-02-5)
• EPA Substance Registry System: 4-Piperidinecarboxaldehyde, 1-(phenylmethyl)-, oxime(88796-02-5)

Safety Data

• Hazardous Substances Data: 88796-02-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 190446-85-6 tert-butyl 4-((hydroxyimino)methyl)piperidine-1-carboxylate 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 

Downstream Products

• 62718-31-4 1-benzylpiperidine-4-carbonitrile 
• 1316307-94-4 methyl 2-(3-((3-(1-benzylpiperidin-4-yl)-4,5-dihydro-isoxazol-5-yl)methyl)-4-oxo-3,4-dihydrophthalazin-1-yl)-3-methoxyacrylate 

Relevant articles and documents

Synthesis of Nitriles from Aldoximes and Primary Amides Using XtalFluor-E

The dehydration reaction of aldoximes and amides for the synthesis of nitriles using [Et2NSF2]BF4 (XtalFluor-E) is described. Overall, the reaction proceeds rapidly (normally 1 h) at room temperature in an environmentally benign solvent (EtOAc) with only a slight excess of the dehydrating agent (1.1 equiv). A broad scope of nitriles can be prepared, including chiral nonracemic ones. In addition, in a number of cases, further purification of the nitrile after the workup was not required.