888-71-1

Basic information

• Product Name: 3,5-diphenyl-1,2,4-oxadiazole
• Synonyms: 3,5-diphenyl-1,2,4-oxadiazole;Diphenyl-1,2,4-oxadiazole
• CAS NO: 888-71-1
• Molecular Formula: C₁₄H₁₀N₂O
• Molecular Weight: 222.25
• Mol File: 888-71-1.mol
• Article Data: 93

Chemical Properties

• Melting Point: 109°C
• Boiling Point: 363.42°C (rough estimate)
• Flash Point: 182.7°C
• Appearance: /
• Density: 1.1400 (rough estimate)
• Vapor Pressure: 1.32E-05mmHg at 25°C
• Refractive Index: 1.5910 (estimate)
• CAS DataBase Reference: 3,5-diphenyl-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diphenyl-1,2,4-oxadiazole(888-71-1)
• EPA Substance Registry System: 3,5-diphenyl-1,2,4-oxadiazole(888-71-1)

Safety Data

• Hazardous Substances Data: 888-71-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H10N2O/c1-3-7-11(8-4-1)13-15-14(17-16-13)12-9-5-2-6-10-12/h1-10H

Upstream product

• 110-86-1 pyridine 
• 75-52-5 nitromethane 
• 98-88-4 benzoyl chloride 
• 572-43-0 1,2-Diphenyl-ethane-1,2-dione dioxime 
• 873-67-6 benzonitrile oxide 
• 100-47-0 benzonitrile 
• 932-90-1 syn-benzaldehyde oxime 
• 13591-25-8 dibenzylidene-diazoxane-N-oxide 
• 19768-02-6 3,4-diphenylfurazan 
• 62-53-3 aniline 
• 64-17-5 ethanol 
• 622-32-2 (Z)-benzaldehyde oxime 
• 64-19-7 acetic acid 
• 522-34-9 Diphenylglyoxime 

Downstream Products

• 103-71-9 phenyl isocyanate 
• 100-47-0 benzonitrile 
• 20844-48-8 3-(3-nitrophenyl)-5-phenyl-1,2,4-oxadiazole 
• 1022-45-3 2-phenyl-4(3H)-quinazolinone 
• 20498-41-3 N-benzoyl-N'-methoxy-benzamidine 
• 16776-73-1 N-benzoylbenzamidine 
• 64017-21-6 3,5-diphenyl-1-methyl-1H-1,2,4-triazole 
• 66130-15-2 N-(methylaminocarbonyl)-N'-phenylbenzamidine 
• 2039-06-7 3,5-diphenyl-1,2,4-triazole 
• 34985-93-8 1-amino-3,5-diphenyl-1,2,4-triazole 
• 17467-15-1 2-amino-4-phenyl-1,3,5-thiadiazole 
• 4115-15-5 3,5-diphenyl-[1,2,4]thiadiazole 
• 16776-73-1 N-benzoyl-benzamidine 
• 7664-41-7 ammonia 

Relevant articles and documents

A Selective Synthesis of 3,5-Diphenyl-1,2,4-Oxadiazole by a Reaction of Benzylcobaloxime with Alkyl Nitrite

Benzyl ligand of Benzylbis(dimethylglyoximato)pyridine cobalt complexe was selectively converted to 3,5-diphenyl-1,2,4-oxadiazole by a reaction with alkyl nitrite under irradiation of visible light.The reaction proceeds via an in situ formation of an oxim

Imidazole hydrochloride promoted synthesis of 3,5-disubstituted-1,2,4-oxadiazoles

Imidazole hydrochloride as an additive promotes the reaction of amidoximes and DMA derivatives to generated 3,5-disubstituted-1,2,4-oxadiazoles in low to excellent yields without the use of coupling reagents, oxidants, strong acids or bases and other additives.

TBAI/TBHP-Catalyzed Synthesis of [1,2,4]Triazolo[4,3-a]pyridines and 3,5-Diaryl-1,2,4-oxadiazoles via Oxidative Cleavage of C=C Double Bond

Abstract: A simple and efficient protocol has been described for the synthesis of [1,2,4]triazolo[4,3-a]pyri-dines and 3,5-disubstituted-1,2,4-oxadiazoles by reacting 2-hydrazinylpyridine and benzamidoximes, respec-tively, with styrenes via TBAI/TBHP-mediated oxidative cleavage of C=C bond under ligand- and metal-free conditions.