88801-90-5

Basic information

• Product Name: (1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol
• CAS NO: 88801-90-5
• Molecular Formula: C₁₁H₁₆N₆O₃S
• Molecular Weight: 312.3481
• Mol File: 88801-90-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 687.4°C at 760 mmHg
• Flash Point: 369.5°C
• Density: 2g/cm³
• Vapor Pressure: 7.68E-20mmHg at 25°C
• Refractive Index: 1.921
• CAS DataBase Reference: (1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol(88801-90-5)
• EPA Substance Registry System: (1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol(88801-90-5)

Safety Data

• Hazardous Substances Data: 88801-90-5(Hazardous Substances Data)

Usage

Description

(1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol is a complex organic molecule characterized by its unique stereochemistry and functional groups. It features a cyclopentane-1,2-diol ring with two hydroxyl groups, and a triazolopyrimidine ring that includes an amino group and a methylsulfanyl group. The specific stereochemistry (1R,2S,3R,5R) denotes the configuration of its asymmetric carbon atoms, which may contribute to its potential pharmaceutical or biological applications.

Uses

Used in Pharmaceutical Industry:
(1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol is used as a potential pharmaceutical compound for its unique structural features. The presence of the cyclopentane-1,2-diol ring, triazolopyrimidine ring, and functional groups such as the amino and methylsulfanyl groups may contribute to its activity against specific biological targets or diseases.
Used in Biological Research:
In the field of biological research, (1R,2S,3R,5R)-3-[5-amino-7-(methylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(hydroxymethyl)cyclopentane-1,2-diol can be utilized as a tool to study the interactions between small molecules and biological systems. Its specific stereochemistry and functional groups may allow for targeted investigations into molecular recognition and binding processes.

Upstream product

• 74-93-1 methylthiol 
• 50619-41-5 2-amino-6-chloro-8-azapurine 

Relevant articles and documents

Synthesis and antiviral evaluation of carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines

Carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines were prepared from the 2-amino-6-chloropurine ribofuranoside analogue and the 2-amino-6-chloro-8-azapurine ribofuranoside analogue, respectively. Analogues of purine ribofuranosides with the chloro, amino, methylamino, or methylthio group at position 6, the thioguanosine analogue, and the previously reported guanosine analogue were evaluated in vitro against herpes simplex virus, type 1 (HSV-1). 8-Azapurine ribofuranoside analogues with the chloro, amino, or methylthio group at position 6 and the previously reported 8-azaguanosine analogue were also evaluated against HSV-1. The carbocyclic analogue of 2,6-diaminopurine ribofuranoside is highly active against HSV-1 and, also, against vaccinia virus. The 2-amino-6-chloropurine, 2-amino-6-(methylamino)purine, and the 2,6-diamino-8-azapurine derivatives also demonstrated significant activity against HSV-1.