888038-31-1

Basic information

• Product Name: 1-(2-Bromo-phenyl)-piperidine-4-carboxylic acid (3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amide
• CAS NO: 888038-31-1
• Molecular Weight: 430.301
• Mol File: 888038-31-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-Bromo-phenyl)-piperidine-4-carboxylic acid (3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Bromo-phenyl)-piperidine-4-carboxylic acid (3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amide(888038-31-1)
• EPA Substance Registry System: 1-(2-Bromo-phenyl)-piperidine-4-carboxylic acid (3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amide(888038-31-1)

Safety Data

• Hazardous Substances Data: 888038-31-1(Hazardous Substances Data)

Upstream product

• 1059536-46-7 1-(2-bromo-phenyl)-piperidine-4-carboxylic acid 
• 89976-75-0 6-amino-2H-1,4-benzoxazin-3(4H)-one 

Relevant articles and documents

Discovery of piperidine carboxamide TRPV1 antagonists

A series of piperidine carboxamides were developed as potent antagonists of the transient receptor potential vanilloid-1 (TRPV1), an emerging target for the treatment of pain. A focused library of polar head groups led to the identification of a benzoxazinone amide that afforded good potency in cell-based assays. Synthesis and a QSAR model will be presented.