88823-34-1

Basic information

• Product Name: (4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine
• Synonyms: 1H-indeno[1,2-b]pyridine, 2,3,4,4a,5,9b-hexahydro-5-phenyl-1-propyl-, (4aS,5R,9bS)-
• CAS NO: 88823-34-1
• Molecular Formula: C₂₁H₂₅N
• Molecular Weight: 291.4299
• Mol File: 88823-34-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 403°C at 760 mmHg
• Flash Point: 176.4°C
• Density: 1.041g/cm³
• Vapor Pressure: 1.05E-06mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: (4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine(88823-34-1)
• EPA Substance Registry System: (4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine(88823-34-1)

Safety Data

• Hazardous Substances Data: 88823-34-1(Hazardous Substances Data)

Usage

Description

(4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine is a complex organic compound belonging to the class of indeno pyridines. It features a polycyclic structure with an indene moiety fused to a pyridine ring, a phenyl group attached to the 5th carbon atom, and a propyl group attached to the 1st carbon atom of the indene ring. The hexahydro-1H-indeno[1,2-b]pyridine structure suggests it is a saturated form of the indole and pyridine ring system, with the stereochemistry (4aS,5R,9bS) indicating the specific arrangement of atoms within the molecule. This unique structure and potential biological activities make it a compound of interest for medicinal chemistry and drug development.

Uses

Used in Medicinal Chemistry:
(4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine is used as a compound in medicinal chemistry for its potential to be developed into a pharmaceutical agent. Its unique structure and stereochemistry may allow it to interact with biological targets in novel ways, potentially leading to the development of new drugs.
Used in Drug Development:
In the field of drug development, (4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine is used as a starting point for designing new therapeutics. Its specific arrangement of atoms and fused ring system may provide a foundation for creating molecules with desired pharmacological properties, such as selectivity, potency, and bioavailability.
Used in Pharmaceutical Research:
(4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine is utilized in pharmaceutical research as a compound with potential biological activities. Researchers may investigate its interactions with various biological targets to understand its pharmacological profile and explore its potential as a therapeutic agent for specific diseases or conditions.
Used in Chemical Synthesis:
In the chemical synthesis industry, (4aS,5R,9bS)-5-phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine may be used as a building block or intermediate in the synthesis of more complex molecules. Its unique structure could be valuable for creating novel compounds with specific properties for various applications, including pharmaceuticals, agrochemicals, or materials science.

Upstream product

• 88687-33-6 (4aR,5R,9bR)-5-Phenyl-1-propyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine; hydrochloride 

Downstream Products

• 107035-09-6 (-)-4aS,5R,9bR-1-n-propyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno<1,2-b>pyridine 
• 107035-10-9 (+)-4aR,5S,9bR-1-n-propyl-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno<1,2-b>pyridine 

Relevant articles and documents

2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridines: Potential antidepressants

The synthesis of various diastereoisomeric H(4a),H5-cis,H(4a),H(9b)-cis- and H(4a),H5-trans,H(4a)H(9b)-cis-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyr idines is described, as well as the evaluation of their antidepressant potency. El