888485-27-6Relevant articles and documents
FUNGICIDAL ARYL AMIDINES
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Paragraph 0083, (2020/12/07)
This disclosure relates to aryl amidines of Formula I and their use as fungicides. One embodiment of the present disclosure is a use of a compound of Formula I, for protection of a plant against attack by a phytopathogenic organism or the treatment of a plant infested by a phytopathogenic organism, comprising the application of a compound of Formula I, or a composition comprising the compound to soil, a plant, a part of a plant, foliage, and/or roots.
The synthesis and characterization of all diastereomers of a linear symmetrically fused tris-troeger's base analogue: New chiral cleft compounds
Artacho, Josep,Nilsson, Patrik,Bergquist, Karl-Erik,Wendt, Ola F.,Waernmark, Kenneth
, p. 2692 - 2701 (2008/02/03)
The synthesis and characterization of all diastereomers of a linear symmetrically fused tris-Troeger's base analogue are described. The diastereomers are unambiguously assigned as syn-anti 1a, anti-anti 1b, and syn-syn 1c isomers, by using X-ray diffraction analysis and NMR spectroscopy. For the first time, the anti-anti and the syn-syn diastereomers of a linear symmetrically fused tris-Troeger's base analogue have been synthesized. Molecules 1a and 1c are new cleft compounds and analysis of compound la in the solid state shows inclusion of one molecule of CH2Cl2 in the largeraromatic cleft, whereas in isomer 1c disordered solvent molecules are trapped in the extended aromatic cleft. Furthermore, in the solid state, isomer 1c forms infinite open channels along one of the crystallographic axes and perpendicular to this axis there are infinitely extending "wedged- ravines". Importantly, each of the diastereomers 1a-c is resistant to inversion at thestereogenic nitrogen atoms under strongly and weakly acidic conditions in the range from room temperature (RT) to 95°C. This observed configurational stability at the stereogenic nitrogens of 1a-c is unique for analogues of Troeger's base in general to date. Finally, the ratio of cleft compounds la and le significantly increased relative to cavity compound 1b when ammonium chloride was used as an additive in the Troeger's base condensation to 1a-c suggesting a templating effect of the ammonium ion.