888494-16-4

Basic information

• Product Name: Glycine, N-[(1R)-1-(hydroxymethyl)propyl]-N-(phenylmethyl)-, 1,1-dimethylethyl ester
• CAS NO: 888494-16-4
• Molecular Formula: C17H27NO3
• Molecular Weight: 293.406
• Mol File: 888494-16-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Glycine, N-[(1R)-1-(hydroxymethyl)propyl]-N-(phenylmethyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[(1R)-1-(hydroxymethyl)propyl]-N-(phenylmethyl)-, 1,1-dimethylethyl ester(888494-16-4)
• EPA Substance Registry System: Glycine, N-[(1R)-1-(hydroxymethyl)propyl]-N-(phenylmethyl)-, 1,1-dimethylethyl ester(888494-16-4)

Safety Data

• Hazardous Substances Data: 888494-16-4(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 40916-80-1 (2R)-2-[N-(benzylideneamino)]-3-methylpropan-1-ol 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 6257-49-4 (2R)-2-(benzylamino)butan-1-ol 

Downstream Products

• 888494-25-5 [benzyl-(2-chloro-butyl)-amino]-acetic acid tert-butyl ester 

Relevant articles and documents

Stereocontrolled synthesis of 3-substituted azetidinic amino acids

A set of enantiomerically pure N-disubstituted β-amino alcohols was chlorinated by treatment with thionyl chloride. This reaction gave a mixture of regioisomeric chlorides that could be equilibrated to the more stable regioisomer by heating in DMF. The chlorides thus obtained were engaged in an intramolecular anionic ring-closure and gave access to fully protected enantio- and diastereomerically pure 2,3-cis-disubstituted azetidinic amino acids. One of the latter was deprotected and included in a short peptide sequence. Georg Thieme Verlag Stuttgart.