889060-82-6 Usage
Description
1-(3-Methylbutyl)-4-aMine piperidine, with the chemical formula C11H23N, is a tertiary amine featuring a piperidine ring and a 3-methylbutyl group, which signifies its branched alkyl amine structure. 1-(3-Methylbutyl)-4-aMine piperidine is recognized for its potential applications in various sectors, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-(3-Methylbutyl)-4-aMine piperidine is utilized as an intermediate in the synthesis of a wide range of drugs, playing a crucial role in the development of novel pharmaceuticals. Its unique structural properties allow it to serve as a building block for creating diverse medicinal compounds.
Used in Research and Development:
In the realm of research and development, 1-(3-Methylbutyl)-4-aMine piperidine is employed for exploring new chemical reactions and understanding its reactivity with different reagents. This helps in expanding the knowledge base of chemical compounds and their potential applications.
Used in Organic Synthesis:
1-(3-Methylbutyl)-4-aMine piperidine may also find applications in organic synthesis, where it can be used to create a variety of organic compounds with different functional groups and properties. Its versatility as a branched alkyl amine makes it a valuable component in the synthesis of complex organic molecules.
Used in Chemical Processes:
Potentially, 1-(3-Methylbutyl)-4-aMine piperidine can be involved in various chemical processes, where its reactivity and structural features can be harnessed to achieve specific outcomes, such as the production of specialty chemicals or materials with unique properties.
Safety Precautions:
It is essential to handle 1-(3-Methylbutyl)-4-aMine piperidine with care, as it is a potentially hazardous material. Proper safety protocols and guidelines should be followed to ensure the safe use and handling of this compound in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 889060-82-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,0,6 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 889060-82:
(8*8)+(7*8)+(6*9)+(5*0)+(4*6)+(3*0)+(2*8)+(1*2)=216
216 % 10 = 6
So 889060-82-6 is a valid CAS Registry Number.
889060-82-6Relevant articles and documents
Discovery of 2-substituted 1H-benzo[d]immidazole-4-carboxamide derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors with in?vivo anti-tumor activity
Zhou, Jie,Ji, Ming,Zhu, Zhixiang,Cao, Ran,Chen, Xiaoguang,Xu, Bailing
, p. 26 - 41 (2017)
Novel 1H-benzo[d]immidazole-4-carboxamide derivatives bearing five-membered or six-membered N-heterocyclic moieties at the 2-position were designed and synthesized as PARP-1 inhibitors. Structure-activity relationships were conducted and led to a number of potent PARP-1 inhibitors having IC50 values in the single or double digit nanomolar level. Some potent PARP-1 inhibitors also had similar inhibitory activities against PARP-2. Among all the synthesized compounds, compound 10a and 11e displayed strong potentiation effects on temozolomide (TMZ) in MX-1?cells (PF50?=?7.10, PF50?=?4.17). In?vivo tumor growth inhibition was investigated using compound 10a in combination with TMZ, and it was demonstrated that compound 10a could strongly potentiate the cytotoxicity of TMZ in MX-1 xenograft tumor model. Two co-crystal structures of compounds 11b and 15e complexed with PARP-1 were achieved and demonstrated a unique binding mode of these benzo-imidazole derivatives.
