889472-40-6

Basic information

• Product Name: 4-Pentenamide, 2-hydroxy-3-methyl-N-phenyl-, (2S,3R)-
• CAS NO: 889472-40-6
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• Mol File: 889472-40-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Pentenamide, 2-hydroxy-3-methyl-N-phenyl-, (2S,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenamide, 2-hydroxy-3-methyl-N-phenyl-, (2S,3R)-(889472-40-6)
• EPA Substance Registry System: 4-Pentenamide, 2-hydroxy-3-methyl-N-phenyl-, (2S,3R)-(889472-40-6)

Safety Data

• Hazardous Substances Data: 889472-40-6(Hazardous Substances Data)

Upstream product

• 17486-12-3 (E)-but-2-en-1-yltrimethylsilane 
• 32331-75-2 2-oxo-N-phenylacetamide 
• 17486-13-4 (Z)-crotyltrimethylsilane 
• 62-53-3 aniline 
• 13209-80-8 N-phenyl-3-methyl-2-butenamide 

Downstream Products

• 889472-57-5 (2S,3R)-2-methanesulfonyloxy-3-methyl-N-phenylpent-4-enamide 
• 55721-65-8 Boc-D-Ile-OH 
• 889472-41-7 [1-(tert-butoxycarbonyl-phenyl-aminocarbonyl)-2-methyl-butyl]-carbamic acid tert-butyl ester 
• 889472-58-6 (2R,3R)-2-azido-3-methyl-N-phenylpent-4-enamide 

Relevant articles and documents

Asymmetric, anti-selective scandium-catalyzed Sakurai additions to glyoxyamide. Applications to the syntheses of N-Boc D-alloisoleucine and D-isoleucine

An enantio- and diastereoselective Sakurai-Hosomi reaction, catalyzed by chiral scandium pyridyl-bis(oxazoline) (pybox) complexes, has been developed. Both alkyl- and aryl-substituted allylsilanes are effective coupling partners with N-phenylglyoxamide. Applications of this reaction to the asymmetric syntheses of N-Boc D-alloisoleucine and D-isoleucine are described.