88975-09-1

Basic information

• Product Name: Propanedioic acid, (2-chloro-4-nitrophenyl)methyl-, diethyl ester
• CAS NO: 88975-09-1
• Molecular Formula: C14H16ClNO6
• Molecular Weight: 329.737
• Mol File: 88975-09-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (2-chloro-4-nitrophenyl)methyl-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (2-chloro-4-nitrophenyl)methyl-, diethyl ester(88975-09-1)
• EPA Substance Registry System: Propanedioic acid, (2-chloro-4-nitrophenyl)methyl-, diethyl ester(88975-09-1)

Safety Data

• Hazardous Substances Data: 88975-09-1(Hazardous Substances Data)

Upstream product

• 99-54-7 3,4-dichloronitrobenzene 
• 609-08-5 Diethyl methylmalonate 

Downstream Products

• 42782-54-7 3-Chloro-4-ethylnitrobenzene 
• 88975-68-2 2-[4-(3-Benzoyl-1-methyl-thioureido)-2-chloro-phenyl]-2-methyl-malonic acid diethyl ester 
• 88975-52-4 2-[4-(3-Benzoyl-thioureido)-2-chloro-phenyl]-2-methyl-malonic acid diethyl ester 
• 88975-30-8 2-[2-Chloro-4-(2,2,2-trifluoro-acetylamino)-phenyl]-2-methyl-malonic acid diethyl ester 
• 93914-68-2 2-(2-Chloro-4-thiocarbamoyloxy-phenyl)-2-methyl-malonic acid diethyl ester 
• 88975-87-5 2-(2-Chloro-4-cyanato-phenyl)-2-methyl-malonic acid diethyl ester 
• 73120-20-4 2-[2-Chloro-4-(methyl-thiazol-2-yl-amino)-phenyl]-propionic acid 
• 88975-20-6 2-(2-Chloro-4-methylamino-phenyl)-2-methyl-malonic acid diethyl ester 
• 88975-40-0 2-(2-Chloro-4-hydroxy-phenyl)-2-methyl-malonic acid diethyl ester 
• 73120-18-0 2-[2-chloro-4-(N-thiazol-2-ylamino)phenyl]propionic acid 
• 56355-35-2 2-(2-chloro-4-thiazol-2-yloxy-phenyl)-propionic acid 
• 83528-19-2 2-[2-Chloro-4-(pyridin-2-ylamino)-phenyl]-propionic acid methyl ester 
• 83528-37-4 2-[2-Chloro-4-(pyridin-2-ylamino)-phenyl]-propionic acid 
• 83528-08-9 methyl 2-(2-chloro-4-nitrobenzene)propionate 

Relevant articles and documents

Bis(dealkoxycarbonylation) of nitroarylmalonates: A facile entry to alkylated nitroaromatics

A simple approach to alkylated nitroaromatics from substituted nitroaryl malonic esters by double decarboxylation is detailed.

Nonsteroidal antiinflammatory agents. 2. [(Heteroarylamino)phenyl]alkanoic acids

A series of [(heteroarylamino)phenyl]alkanoic acids pyridine, quinoline, or pyrimidine as the heteroaryl moiety was prepared as potential antiinflammatory agents. Among them, 2-[4-(2-pyridylamino)phenyl]propionic acid (14b) showed excellent antiinflammatory and analgesic activities with less tendency to cause gastric side effects. Structure-activity relationships are discussed.