889849-24-5

Basic information

• Product Name: (4-bromo-2-fluoro-phenyl)-(4-bromo-2-methyl-2H-pyrazol-3-yl)-amine
• Synonyms: (4-bromo-2-fluoro-phenyl)-(4-bromo-2-methyl-2H-pyrazol-3-yl)-amine
• CAS NO: 889849-24-5
• Molecular Weight: 349
• Mol File: 889849-24-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-bromo-2-fluoro-phenyl)-(4-bromo-2-methyl-2H-pyrazol-3-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromo-2-fluoro-phenyl)-(4-bromo-2-methyl-2H-pyrazol-3-yl)-amine(889849-24-5)
• EPA Substance Registry System: (4-bromo-2-fluoro-phenyl)-(4-bromo-2-methyl-2H-pyrazol-3-yl)-amine(889849-24-5)

Safety Data

• Hazardous Substances Data: 889849-24-5(Hazardous Substances Data)

Upstream product

• 216393-64-5 (4-bromo-2-fluorophenyl)boronic acid 
• 105675-85-2 4-bromo-2-methyl-2H-pyrazol-3-ylamine 

Relevant articles and documents

PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to certain pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like. The present invention also relates to the methods for the treatment of 5-HT2A serotonin receptor mediated disorders in combination with other pharmaceutical agents administered separately or together.