889939-92-8

Basic information

• Product Name: 2-(1-methylpiperazin-2-yl)ethanol
• Synonyms: 2-(1-methylpiperazin-2-yl)ethanol(SALTDATA: FREE);2-(1-Methylpiperazin-2-yl)ethan-1-ol
• CAS NO: 889939-92-8
• Molecular Formula: C7H16N2O
• Molecular Weight: 144.22
• Mol File: 889939-92-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 239.2 °C at 760 mmHg
• Flash Point: 98.5 °C
• Appearance: /
• Density: 0.97g/cm³
• Vapor Pressure: 0.00715mmHg at 25°C
• Refractive Index: 1.462
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-(1-methylpiperazin-2-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methylpiperazin-2-yl)ethanol(889939-92-8)
• EPA Substance Registry System: 2-(1-methylpiperazin-2-yl)ethanol(889939-92-8)

Safety Data

• Hazardous Substances Data: 889939-92-8(Hazardous Substances Data)

Usage

General Description

2-(1-methylpiperazin-2-yl)ethanol, also known as N-methyl-2-(1-piperazinyl)ethyl alcohol, is a chemical compound with the molecular formula C8H18N2O. It is a colorless liquid at room temperature and is commonly used as a solvent and intermediate in the production of various pharmaceuticals and organic compounds. 2-(1-methylpiperazin-2-yl)ethanol has a wide range of applications, including its use as a precursor in the synthesis of antihistamine medications, antipsychotic drugs, and other pharmaceuticals. Additionally, 2-(1-methylpiperazin-2-yl)ethanol is also used in the manufacturing of dyes, insecticides, and other organic compounds. It is important to handle this compound with care, as it can be harmful if ingested, inhaled, or comes into contact with the skin. Proper safety measures should be taken when handling and storing this chemical.

InChI:InChI=1/C7H16N2O/c1-9-4-3-8-6-7(9)2-5-10/h7-8,10H,2-6H2,1H3

Upstream product

• 534603-30-0 methyl 2-(1-methyl-3-oxopiperazin-2-yl)acetate 

Downstream Products

• 1462950-83-9 2-{1-methyl-4-[4-nitro-3-(propan-2-yloxy)phenyl]piperazin-2-yl}ethanol 

Relevant articles and documents

OXAZOLE TYROSINE KINASE INHIBITORS

The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1 : provided that the sum of a and b is 0 or 1; T is O or NH Ar1 is a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S, and being optionally substituted by one or more substituents R1; Ar2 Js a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S and being optionally substituted by one or more substituents R2; and R1 and R2are as defined in the claims. The compounds are inhibitors of kinases and in particular FLT3, FLT4 and Aurora kinases.