89084-30-0

Basic information

• Product Name: 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-(diphenylphosphinyl)-
• CAS NO: 89084-30-0
• Molecular Formula: C22H19O4P
• Molecular Weight: 378.364
• Mol File: 89084-30-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-(diphenylphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-(diphenylphosphinyl)-(89084-30-0)
• EPA Substance Registry System: 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-(diphenylphosphinyl)-(89084-30-0)

Safety Data

• Hazardous Substances Data: 89084-30-0(Hazardous Substances Data)

Upstream product

• 4736-60-1 ethyltriphenylphosphonium iodide 
• 94-53-1 Piperonylic acid 
• 6951-08-2 ethyl 1,3-benzodioxole-5-carboxylate 
• 1733-57-9 ethydiphenylphosphine oxide 
• 326-56-7 methyl 3,4-methylenedioxybenzoate 

Downstream Products

• 17627-76-8 (Z)-5-(prop-1-en-1-yl)benzo[d][1,3]dioxole 
• 78266-84-9 (1RS,2RS)-2-diphenylphosphinoyl-1-(3,4-methylenedioxyphenyl)propan-1-ol 
• 78266-84-9 (1RS,2SR)-2-diphenylphosphinoyl-1-(3,4-methylenedioxyphenyl)propan-1-ol 
• 78266-84-9 1-Benzo[1,3]dioxol-5-yl-2-(diphenyl-phosphinoyl)-propan-1-ol 
• 78266-84-9 1-Benzo[1,3]dioxol-5-yl-2-(diphenyl-phosphinoyl)-propan-1-ol 

Relevant articles and documents

The Stereocontrolled Horner-Wittig Reaction: Synthesis of Disubstituted Alkenes

Addition of the lithium derivatives of phosphine oxides Ph2P(O)CH2R1 to aldehydes gives erythro adducts (11) with good stereoselectivity.Reduction of α-diphenylphosphinoyl ketones (12) gives threo adducts (11) with even better stereoselectivity.Purification by flash chromatography and/or crystallisation followed by elimination of Ph2PO2 gives pure Z- or E-alkenes with high material conversion.Explanations are offered for the stereoselectivities, conditions defined for full stereochemical control, and guidelines suggested for approaches to a given alkene.