89091-84-9

Basic information

• Product Name: 1-Hexanone, 2-(diphenylphosphinyl)-1-phenyl-
• CAS NO: 89091-84-9
• Molecular Formula: C24H25O2P
• Molecular Weight: 376.435
• Mol File: 89091-84-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Hexanone, 2-(diphenylphosphinyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hexanone, 2-(diphenylphosphinyl)-1-phenyl-(89091-84-9)
• EPA Substance Registry System: 1-Hexanone, 2-(diphenylphosphinyl)-1-phenyl-(89091-84-9)

Safety Data

• Hazardous Substances Data: 89091-84-9(Hazardous Substances Data)

Upstream product

• 93-89-0 benzoic acid ethyl ester 
• 88533-60-2 (n-pentyl)diphenylphosphane oxide 
• 603-35-0 triphenylphosphine 
• 21406-61-1 pentyltriphenylphosphonium bromide 
• 110-53-2 1-Bromopentane 
• 2129-89-7 diphenyl(methyl)phosphine oxide 
• 93-58-3 benzoic acid methyl ester 
• 109-65-9 1-bromo-butane 
• 1733-58-0 phenacyldiphenylphosphine oxide 
• 542-69-8 1-iodo-butane 

Downstream Products

• 6111-82-6 (E)-1-phenyl-1-hexene 
• 15325-54-9 (Z)-hex-1-en-1-ylbenzene 
• 88533-65-7 threo-2-diphenylphosphinoyl-1-phenylhexan-1-ol 
• 88533-65-7 erythro-2-diphenylphosphinoyl-1-phenylhexan-1-ol 
• 88533-65-7 2-(Diphenyl-phosphinoyl)-1-phenyl-hexan-1-ol 
• 88533-65-7 2-(Diphenyl-phosphinoyl)-1-phenyl-hexan-1-ol 

Relevant articles and documents

Diphenylphosphinoyl-mediated synthesis of ketones

α-Diphenylphosphinoyl ketones are selectively and sequentially alkylated at the α-position. Double lithiation and selective alkylation occurs at the less stabilised γ-position. Dephosphinoylation of the alkylation products gives ketones. Mono-alkylation is selective, highly crystalline intermediates are formed and a one-pot strategy is possible. The method is ideally suited for the preparation of acid-sensitive ketones. The Royal Society of Chemistry 2006.

TRANS ALKENES BY STEREOSELECTIVE REDUCTION OF α-Ph2PO KETONES: E-ISOSAFFROLE, E-ANETHOLE, AND FENICULIN

Conditions are described for the stereoselective reduction of α-Ph2PO ketones and stereospecific elimination from the resulting threo Horner-Witting intermediates to give pure E-alkenes such as the title compounds.