890929-78-9

Basic information

• Product Name: 4-bromo-1-((2-chloroethoxy)methyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile
• Synonyms: 4-bromo-1-((2-chloroethoxy)methyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile
• CAS NO: 890929-78-9
• Molecular Weight: 442.062
• Mol File: 890929-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-bromo-1-((2-chloroethoxy)methyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-((2-chloroethoxy)methyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile(890929-78-9)
• EPA Substance Registry System: 4-bromo-1-((2-chloroethoxy)methyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile(890929-78-9)

Safety Data

• Hazardous Substances Data: 890929-78-9(Hazardous Substances Data)

Upstream product

• 122454-23-3 2-(p-chlorophenyl)-5-(trifluoromethyl)-pyrrole-3-carbonitrile 
• 1462-33-5 2-chloroethyl chloromethyl ether 
• 122454-29-9 tralopyril 
• 6212-33-5 2-(4-Chlorophenyl)glycine 
• 122460-66-6 4-(p-chlorophenyl)-2-(trifluoromethyl)-1,3-oxazol-5-one 
• 627-42-9 2-chloroethyl methyl ether 

Downstream Products

• 890929-85-8 4-bromo-2-(4-chlorophenyl)-1-((2-(methylsulfinyl)ethoxy)methyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile 
• 890929-86-9 4-bromo-2-(4-chlorophenyl)-1-((2-(methylsulfonyl)ethoxy)methyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile 
• 890929-79-0 4-bromo-2-(4-chlorophenyl)-1-((2-(methylthio)ethoxy)methyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile 

Relevant articles and documents

Application of 2-aryl substituted pyrrole compound in medicine for killing oncomelania hupensis

The invention relates to an application of 2-aryl substituted pyrrole compound in a medicine for killing oncomelania hupensis and belongs to the technical field of prevention and treatment of bilharziasis, and particularly provides the chemical structure of the 2-aryl substituted pyrrole compound and a preparation method of same. The 2-aryl substituted pyrrole compound, being an active component,is used for preparing the snail killing agent in the forms of suspending agents, emulsions and micro-emulsions for killing the oncomelania hupensis. Immersion killing use amount of the 2-aryl substituted pyrrole compound being the active component of the snail killing agent is 0.1-10.00 mg/l, and immersion killing time is 24-72 h. The use amount of spray application is 1-10 g/m and action timeis 3-7 days. Experiment proves that the 2-aryl substituted pyrrole compound has killing activity on the oncomelania hupensis and is lower than a snail killing agent, niclosamide, in the prior art in toxicity on aquatic organisms. The compound can be processed to prepare the snail killing agents and applied in the field of prevention and treatment of bilharziasis.

Synthesis, insecticidal and acaricidal activities of novel 2-arylpyrroles

To search for novel 2-arylpyrroles with unique biological activities, a series of novel 2-arylpyrrole derivatives were designed and synthesized, and their structures were characterized by 1H and 13C NMR spectroscopy, MS spectrometry, and elemental analysis. Their insecticidal activities against Lepidopteran pests (e.g. Mythimna separata) and acaricidal activities against mites (e.g. Tetranychus urticae) were evaluated. The results of bioassays indicate that some of these title compounds exhibited excellent insecticidal and acaricidal activities. For example, 4-bromo-1-((chloromethoxy) methyl)-2-(4-chloro phenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile (6a), 4-bromo-2-(4-chlorophenyl)-1-((2-fluoroethoxy)-methyl)-5-(trifluoromethyl) pyrrole-3-carbonitrile (6d) showed insecticidal activity against Mythimna separata and 4-bromo-2-(4-chlorophenyl)-1-((isopropoxymethoxy)methyl)-5- (trifluoro methyl)pyrrole-3-carbonitrile (7d) showed acaricidal activity against Tetranychus urticae. They were more effective than Chlorfenapyr, which has been the only commercialized member of a new class of chemicals of 2-arylpyrroles.