89179-86-2

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 5-(aminomethyl)- (9CI)
• Synonyms: 2,4(1H,3H)-Pyrimidinedione, 5-(aminomethyl)- (9CI);5-(aminomethyl)-2,4(1H,3H)-pyrimidinedione
• CAS NO: 89179-86-2
• Molecular Formula: C₅H₇N₃O₂
• Molecular Weight: 141.12798
• Product Categories: PYRIMIDINE
• Mol File: 89179-86-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 5-(aminomethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 5-(aminomethyl)- (9CI)(89179-86-2)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 5-(aminomethyl)- (9CI)(89179-86-2)

Safety Data

• Hazardous Substances Data: 89179-86-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 9, p. 119, 1961 DOI: 10.1248/cpb.9.119

Upstream product

• 876495-24-8 5-isocyanatomethyl-1H-pyrimidine-2,4-dione 
• 856152-76-6 2-ethylmercapto-5-isocyanatomethyl-3H-pyrimidin-4-one 
• 3590-48-5 5-chloromethyluracil 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 4433-40-3 5-hydroxymethyl uracil 

Relevant articles and documents

Uracil derivatives as inhibitors of TNF-alpha converting enzyme (TACE) and matrix metalloproteinases

The present application describes novel uracil derivatives of formula I: A-W-U-X-Y-Z-Ua-Xa-Ya-Za??I or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, W, U, X, Y, Z, Ua, Xa, Ya, and Za are defined in the present specification, which are useful as inhibitors of TNF-α converting enzyme (TACE), matrix metalloproteinases (MMP), aggrecanase or a combination thereof.