89211-06-3Relevant articles and documents
A New Procedure for the One-Carbon Homologation of Ketones to α-Hydroxy Aldehydes
Adamczyk, Maciej,Dolence, E. Kurt,Watt, David S.,Christy, M. Robert,Reibenspies, Joseph H.,Anderson, Oren P.
, p. 1378 - 1382 (2007/10/02)
A new, one-carbon homologation procedure for the conversion of ketones to α-hydroxy aldehydes involves two steps: (1) Darzens condensation of ketones with chloromethyl phenyl sulfone; (2) ring opening of the intermediate α,β-epoxy sulfones with hydroxide