89242-54-6Relevant articles and documents
Palladium(II)-Catalyzed Three-Component Tandem Cyclization Reaction for the One-Pot Assembly of 4-Arylquinazolines
Wang, Zijuan,Chen, Wenteng,He, Chang,Zhang, Guolin,Yu, Yongping
, p. 1356 - 1364 (2020/11/09)
A one-pot method for joining three separate components leading to an assortment of 4-arylquinazolines (27 examples) in good to excellent yields is described. The method consists of a palladium(II)-catalyzed?-cascade reaction involving C(sp)-C(sp 2/s
Quinazoline fluorescent probe and preparation method and application thereof
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, (2020/02/27)
The invention belongs to the technical field of biomedicine and particularly relates to a quinazoline fluorescent probe and a preparation method and application thereof. The chemical formula of the quinazoline fluorescent probe is shown in the formula I, wherein R is selected from H or Cl; R is selected from fluorescent molecules; and n is an integer from 2 to 8. Through the quinazoline fluorescent probe and the preparation method and application thereof, the interference of autofluorescence of an organism can be eliminated, and the TSPO content in the organism can be detected efficiently and accurately.
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO)
Milite, Ciro,Barresi, Elisabetta,Da Pozzo, Eleonora,Costa, Barbara,Viviano, Monica,Porta, Amalia,Messere, Anna,Sbardella, Gianluca,Da Settimo, Federico,Novellino, Ettore,Cosconati, Sandro,Castellano, Sabrina,Taliani, Sabrina,Martini, Claudia
, p. 7897 - 7909 (2017/10/06)
The quinazoline class was exploited to search for a new translocator protein (TSPO) fluorescent probe endowed with improved affinity and residence time (RT). Computational studies on an "in-house" collection of quinazoline derivatives, featuring highly st