89246-30-0 Usage
General Description
2-Bromo-1-methyl-1H-indole is a chemical compound with the molecular formula C9H8BrN. It is an indole derivative with a bromine atom and a methyl group attached to the indole ring. 2-broMo-1-Methyl-1H-Indole is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacturing of dyes and other organic compounds. 2-Bromo-1-methyl-1H-indole may also have potential applications in the field of medicinal chemistry and drug discovery due to its structural and chemical properties. However, it is important to handle this compound with care due to its potential hazards and toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 89246-30-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,4 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 89246-30:
(7*8)+(6*9)+(5*2)+(4*4)+(3*6)+(2*3)+(1*0)=160
160 % 10 = 0
So 89246-30-0 is a valid CAS Registry Number.
89246-30-0Relevant articles and documents
Stereoselective synthesis of spirocyclic oxindoles based on a one-pot Ullmann coupling/Claisen rearrangement and its application to the synthesis of a hexahydropyrrolo[2,3-b]indole alkaloid
Miyamoto, Hiroshi,Hirano, Tomohiro,Okawa, Yoichiro,Nakazaki, Atsuo,Kobayashi, Susumu
supporting information, p. 9481 - 9493 (2013/10/08)
An efficient and convenient approach to the synthesis of spirocyclic oxindoles from iodoindoles has been developed. The most striking feature of this approach is that the sequential intramolecular Ullmann coupling and Claisen rearrangement proceeds in a one-pot manner to afford 3-spiro-2-oxindoles in good yield with excellent diastereoselectivity. Application of this one-pot reaction to chiral non-racemic tertiary alcohol substrates resulted in complete chirality transfer to the spirocyclic quaternary carbon. Using this method, asymmetric total synthesis of (-)-debromoflustramine B was accomplished.
