89358-53-2Relevant articles and documents
Stereoselective intramolecular acylation of y'-benzoyloxyphosphine oxides with an internal chlorotrimethylsilane trap: Isolation of silylated tetrahedral intermediates
Feeder, Neu,Hutton, Gordon,Nelson, Adam,Warren, Stuart
, p. 3413 - 3424 (1999)
The kinetic products of the intramolecular acylation of y'-benzoyloxyphosphine oxides were revealed by conducting the reaction in the presence of an internal trapping agent. A high level of stereocontrol over the formation of both ' : ' the stereogenic centre a to phosphorus and the hemiacetal centre was observed. The stereochemistry of the products was determined by X-ray crystallography and 'H NMR and the stereoselectivity of the reaction is explained in terms of the known structure and configurational instability of lithiated phosphine oxides. The Royal Society of Chemistry 1999.
Synthesis of β-(Diphenylphosphinoyl) Ketones
Bell, Andrew,Davidson, Alan H.,Earnshaw, Chris,Norrish, Howard K.,Torr, Richard S.,et al.
, p. 2879 - 2892 (2007/10/02)
The title compounds may be made by addition of phosphorus nucleophiles (Ph2PO-, Ph2POMgX, Ph2PCl) to enones, by addition of phosphorus-stabilised carbanions to a α-carbonyl cation equivalents (2,3-dichloropropene, epoxides, and α-MeO-ketones) and by oxidation of allyl diphenylphosphine oxides.
