89365-48-0

Basic information

• Product Name: 1,2,4-tribromo-5-nitrobenzene
• CAS NO: 89365-48-0
• Molecular Formula: C₆H₂Br₃NO₂
• Molecular Weight: 359.7976
• Mol File: 89365-48-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 314°C at 760 mmHg
• Flash Point: 143.7°C
• Density: 2.401g/cm³
• Vapor Pressure: 0.000885mmHg at 25°C
• Refractive Index: 1.668
• CAS DataBase Reference: 1,2,4-tribromo-5-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-tribromo-5-nitrobenzene(89365-48-0)
• EPA Substance Registry System: 1,2,4-tribromo-5-nitrobenzene(89365-48-0)

Safety Data

• Hazardous Substances Data: 89365-48-0(Hazardous Substances Data)

Usage

Appearance

Yellow crystalline solid

Usage

Intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds

Classification

Nitrobenzene derivative

Structure

Contains three bromine atoms and one nitro group attached to a benzene ring

Solubility

Insoluble in water, soluble in organic solvents (e.g., acetone and ethanol)

Application

Primarily used in industrial chemical processes and research laboratories

Safety

Toxic, may cause skin and eye irritation, should be handled with care

Upstream product

• 58683-70-8 1,2,4-tribromo-5-isopropyl-benzene 
• 615-54-3 1,2,4-tribromobenzene 
• 98-82-8 Isopropylbenzene 
• 3638-73-1 2,5-dibromoaniline 
• 108-36-1 1,3-dibromobenzene 
• 5411-50-7 3,4-dibromonitrobenzene 
• 615-57-6 2,4-dibromo-aniline 
• 51686-78-3 2,4-dibromonitrobenzene 
• 615-55-4 3,4-dibromoaniline 

Downstream Products

• 636-28-2 1,2,4,5-tetrabromobenzene 
• 615-86-1 2,4,5-tribromoaniline 
• 75293-97-9 2-nitro-4,5-dibromoaniline 
• 265662-22-4 4,5-dibromo-N-isobutyl-2-nitroaniline 
• 649763-38-2 2-amino-4,5-dibromo-N⁽¹⁾-isobutylaniline 
• 265662-25-7 isobutyl-{2-nitro-4,5-bis-[(triisopropylsilanyl)-ethynyl]-phenyl}-amine 
• 1616359-34-2 C₉H₁₀Br₂N₂O₃ 
• 1616359-50-2 4,5-dibromo-1-N-(propan-2-yl)benzene-1,2-diamine 
• 1616359-55-7 C₉H₁₀Br₂N₂O₂ 
• 1616359-53-5 C₁₅H₁₉Br₂N₃O₄ 

Relevant articles and documents

Model Systems for Flavoenzyme Activity: Relationships between Cofactor Structure, Binding and Redox Properties

A series of flavins were synthesized bearing electron-withdrawing and -donating substituents. The electrochemical properties of these flavins in a nonpolar solvent were determined. The recognition of these flavins by a diamidopyridine (DAP) receptor and the effect this receptor has on flavin redox potential was also quantified. It was found that the DAP-flavin binding affinity and the reduction potentials (E1/2) for both the DAP-bound and unbound flavins correlated well with functions derived from linear free energy relationships (LFERs). These results provide insight and predictive capability for the interplay of electronics and redox state-specific interactions for both abiotic and enzymatic systems.

Synthesis and redox properties of novel alkynyl flavins

The synthesis of C7 and/or C8 alkynyl flavins is described. The yields range from 14-48% over six steps. The reduction potentials of these compounds are in good agreement with the values expected based on the Hammett substituent coefficients. (C) 2000 Els