89380-70-1

Basic information

• Product Name: 4-Hydroxypyridine-3-carboxaldehyde
• Synonyms: 4-Hydroxypyridine-3-carboxaldehyde;4-hydroxy-3-Pyridinecarboxaldehyde;4-Hydroxynicotinaldehyde
• CAS NO: 89380-70-1
• Molecular Formula: C₆H₅NO₂
• Molecular Weight: 123.11
• Mol File: 89380-70-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 277.3oC at 760 mmHg
• Flash Point: 143.2oC
• Appearance: /
• Density: 1.365g/cm3
• Vapor Pressure: 0.00455mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.45±0.18(Predicted)
• CAS DataBase Reference: 4-Hydroxypyridine-3-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxypyridine-3-carboxaldehyde(89380-70-1)
• EPA Substance Registry System: 4-Hydroxypyridine-3-carboxaldehyde(89380-70-1)

Safety Data

• Hazardous Substances Data: 89380-70-1(Hazardous Substances Data)

Usage

General Description

4-Hydroxypyridine-3-carboxaldehyde is a chemical compound with the molecular formula C6H5NO2. It is a yellow crystalline solid that is used in the synthesis of pharmaceuticals and other organic compounds. 4-Hydroxypyridine-3-carboxaldehyde has been studied for its potential use in the treatment of various diseases, including cancer, due to its ability to inhibit certain enzymes and proteins. It is also used in the production of agrochemicals and as a reagent in organic chemistry reactions. 4-Hydroxypyridine-3-carboxaldehyde is considered to be toxic if ingested or inhaled and should be handled with care.

InChI:InChI=1/C6H5NO2/c8-4-5-3-7-2-1-6(5)9/h1-4H,(H,7,9)

Upstream product

• 114077-82-6 4-chloronicotinaldehyde 
• 626-61-9 4-Chloropyridine 
• 7379-35-3 4-chlorpyridine hydrochloride 

Downstream Products

• 142890-84-4 3-(hydroxymethyl)-4(1H)-pyridone 
• 116922-80-6 6-azacoumarin 
• 1022156-58-6 2-(4-hydroxypyridin-3-yl)-8-oxo-9-(2-(trifluoromethyl)phenyl)-8,9-dihydro-7H-purine-6-carboxamide 

Relevant articles and documents

HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF

Disclosed herein are compounds, compositions, and methods for reactivating or realkylating aged acetylcholinesterase inhibited by or conjugated to the organophosphorus compound. The organophosphorus compound can be a nerve agent. The acetylcholinesterase can be in the central nerve system (CNS) and/or the peripheral nervous system (PNS) of a subject. Accordingly, methods for ameliorating, diminishing, reversing, treating or preventing the toxic effects of an organophosphorus compound in a subject are provided herein. Methods for prophylactic or therapeutic treatment of exposure to an organophosphorus nerve agent are also provided.

CHEMICAL MOLECULES THAT INHIBIT THE SLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES

The present invention relates to a compound of one of the formulas I to XXI; a pharmaceutical composition comprising at least one such compound; and the use of at least one such compound in preparing a drug to treat, in a subject, a genetic disease resulting from at least one splicing anomaly.

Synthesis and AMPA receptor antagonistic activity of a novel class of quinoxalinecarboxylic acid with a substituted phenyl group at the C-7 position

The synthesis and biological properties of a novel class of 7-heterocycle-substituted quinoxalinecarboxylic acids, which bear a substituted phenyl group through a urethane linkage at the C-7 position, are described. One of the synthesized compounds, 15l,