894-56-4

Basic information

• Product Name: 1-[(4-chlorophenyl)benzyl]piperazinium chloride
• Synonyms: 1-[(4-chlorophenyl)benzyl]piperazinium chloride;Einecs 212-972-5;1-((4-chlorophenyl)(phenyl)Methyl)piperazine hydrochloride;Piperazine, 1-[(4-chlorophenyl)phenylMethyl]-, Monohydrochloride
• CAS NO: 894-56-4
• Molecular Formula: C17H20Cl2N2
• Molecular Weight: 323.2601
• EINECS: 212-972-5
• Mol File: 894-56-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 422.5°C at 760 mmHg
• Flash Point: 209.3°C
• Appearance: /
• Vapor Pressure: 1.53E-07mmHg at 25°C
• CAS DataBase Reference: 1-[(4-chlorophenyl)benzyl]piperazinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(4-chlorophenyl)benzyl]piperazinium chloride(894-56-4)
• EPA Substance Registry System: 1-[(4-chlorophenyl)benzyl]piperazinium chloride(894-56-4)

Safety Data

• Hazardous Substances Data: 894-56-4(Hazardous Substances Data)

Usage

Chemical class

Quaternary ammonium compounds

Derivative of

Piperazine

Potential use

Vasodilator

Potential use

Improving microcirculation

Investigated for

Smooth muscle relaxation

Investigated for

Treatment of hypertension

Investigated for

Antifungal properties

Investigated for

Antibacterial properties

Common form

Chloride salt, used in experimental research and pharmaceutical development

InChI:InChI=1/C18H21ClN2.ClH/c1-20-11-13-21(14-12-20)18(15-5-3-2-4-6-15)16-7-9-17(19)10-8-16;/h2-10,18H,11-14H2,1H3;1H/t18-;/m1./s1

Upstream product

• 454217-55-1 1-[(4-chlorophenyl)phenylmethyl]-4-(tert-butoxycarbonyl)-piperazine 
• 303-26-4 N-(4-chlorobenzhydryl)piperazine 

Relevant articles and documents

OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES

The present invention is related to l-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of l-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. l-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients.

Optically active 4-(tert-butoxycarbonyl) piperazine compound, and method for producing the same

There is provided a 4-(tert-butoxycarbonyl)piperazine compound of formula (1) wherein X denotes a chlorine atom, a C1-C3 alkyl group or a C1-C3 alkoxy group, and optical isomers present therein. Compound of formula (1) is used in the separation of the ena