89402-29-9

Basic information

• Product Name: 2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine
• Synonyms: 2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine
• CAS NO: 89402-29-9
• Molecular Formula: C₆H₂BrF₄N
• Molecular Weight: 243.9843928
• Mol File: 89402-29-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 187.9 °C at 760 mmHg
• Flash Point: 67.5 °C
• Appearance: /
• Density: 1.786 g/cm³
• Vapor Pressure: 0.848mmHg at 25°C
• Refractive Index: 1.4640
• Storage Temp.: 2-8°C
• Solubility: Not miscible or difficult to mix.
• PKA: -4.06±0.20(Predicted)
• CAS DataBase Reference: 2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine(89402-29-9)
• EPA Substance Registry System: 2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine(89402-29-9)

Safety Data

• Hazardous Substances Data: 89402-29-9(Hazardous Substances Data)

Usage

Uses

2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine is used as a pharmaceutical intermediate.

InChI:InChI=1/C6H2BrF4N/c7-5-4(8)1-3(2-12-5)6(9,10)11/h1-2H

Upstream product

• 89402-28-8 3-Fluoro-5-(Trifluoromethyl)Picolinic Acid 
• 21908-53-2 mercury(II) oxide 
• 1040683-15-5 3-fluoro-5-(trifluoromethyl)pyridin-2-ol 
• 80194-70-3 3-chloro-2-cyano-5-(trifluoromethyl)pyridine 

Downstream Products

• 80194-71-4 3-fluoro-5-(trifluoromethyl)picolinonitrile 
• 89402-28-8 3-Fluoro-5-(Trifluoromethyl)Picolinic Acid 
• 1441144-24-6 3-[[3-[[4-chloro-2-[1-[3-fluoro-5-(trifluoromethyl)-2-pyridyl]pyrazole-4-carbonyl]phenyl]carbamoyl]phenyl]methylsulfanyl]propanoic acid 
• 1450819-70-1 N-[4-chloro-2-[1-[3-fluoro-5-(trifluoromethyl)-2-pyridyl]pyrazole-4-carbonyl]phenyl]-3-(piperazin-1-ylmethyl)benzamide 
• 1441144-43-9 N-[4-chloro-2-[1-[3-fluoro-5-(trifluoromethyl)-2-pyridyl]pyrazole-4-carbonyl]phenyl]-3-(piperazin-1-ylmethyl)benzamide 

Relevant articles and documents

CYCLOBUTYL SUBSTITUTED PYRROLOPYRIDINE AND PYRROLOPYRIMIDINE DERIVATIVES AS JAK INHIBITORS

The present invention provides cyclobutyl substituted pyrrolopyrimidines and pyrrolopyridines of Formula I: wherein X, Y, Z, L, A, R5, n and m are defined above, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.

Pyridyl(oxy/thio)phenoxy compounds herbicidal compositions and methods

Certain novel pyridinyloxyphenoxy alkanoic acids, pyridinylthiophenoxy alkanoic acids, derivatives thereof and related compounds are described. More specifically, these novel compounds bear a fluorine substituent in the 3-position of the pyridinyl group and in the 5-position the substituent is selected from chlorine, CF3, CF2 Cl or CF2 H. These novel compounds exhibit surprising preemergent and postemergent activity in the control of grassy weeds.

Pyridyl(oxy/thio)phenoxy compounds, herbicidal compositions and methods

Certain novel pyridinyloxyphenoxy alkanoic acids, pyridinylthiophenoxy alkanoic acids, derivatives thereof and related compounds are described. More specifically, these novel compounds bear a fluorine substituent in the 3-position of the pyridinyl group and in the 5-position the substituent is selected from chlorine, CF3, CF2 Cl or CF2 H. These novel compounds exhibit surprising preemergent and postemergent activity in the control of grassy weeds.