89408-81-1

Basic information

• Product Name: (1S)-1-[(2R)-oxiran-2-yl]hexan-1-ol
• Synonyms: (1S)-1-[(2R)-oxiran-2-yl]hexan-1-ol
• CAS NO: 89408-81-1
• Molecular Weight: 144.214
• Mol File: 89408-81-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1S)-1-[(2R)-oxiran-2-yl]hexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-1-[(2R)-oxiran-2-yl]hexan-1-ol(89408-81-1)
• EPA Substance Registry System: (1S)-1-[(2R)-oxiran-2-yl]hexan-1-ol(89408-81-1)

Safety Data

• Hazardous Substances Data: 89408-81-1(Hazardous Substances Data)

Upstream product

• 3391-86-4 1-octen-3-ol 

Downstream Products

• 522592-42-3 (S)-2-[(R)-1-(2-Vinyl-phenoxy)-hexyl]-oxirane 
• 84435-13-2 (+)-(2S)-2-hydroxyoctan-3-one 
• 96857-03-3 (2S,3R)-2,3-octanediol 2-benzyl ether 
• 96857-04-4 (S)-2-benzyloxy-3-octanone 
• 96857-02-2 (2S,3R)-2,3-octanediol 2-benzyl-3-EE ether 
• 96895-74-8 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-(S)-1-oxiranyl-hexyl ester 
• 96895-73-7 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-(S)-1-oxiranyl-hexyl ester 
• 96857-06-6 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-1-methyl-2-oxo-heptyl ester 
• 96857-05-5 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-1-methyl-2-oxo-heptyl ester 
• 96895-72-6 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-(S)-1-oxiranyl-hexyl ester 
• 96856-97-2 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-(S)-1-oxiranyl-hexyl ester 
• 1390618-97-9 (S)-2-((R)-1-((4-methoxybenzyl)oxy)hexyl)oxirane 
• 1609651-99-1 ((3R)-3-((3S,4R)-4-((4-methoxybenzyl)oxy)-3-(methoxymethoxy)nonyl)oxiran-2-yl)methanol 
• 1609651-98-0 (6S,7R,E)-7-((4-methoxybenzyl)oxy)-6-(methoxymethoxy)dodec-2-en-1-ol 

Relevant articles and documents

The first stereoselective total synthesis of the Z-isomer of cytospolide e

A convergent and highly stereoselective total synthesis of the Z-isomer of cytospolide E has been achieved via Evan's aldol reaction, Sharpless kinetic resolution and RCM cyclisation.

Site-specific synthesis and reactivity of oligonucleotides containing stereochemically defined 1,N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-Hydroxynonenal

trans-4-Hydroxynonenal (HNE) is a major peroxidation product of ω-6 polyunsaturated fatty acids. The reaction of HNE with DNA gives four diastereomeric 1,N2-γ-hydroxypropano adducts of deoxyguanosine; background levels of these adducts have been detected in animal tissue. Stereospecific syntheses of these four adducts at the nucleoside level have been accomplished. In addition, a versatile strategy for their site-specific incorporation into oligonucleotides has been developed. These adducts are destabilizing as measured by melting temperature when compared to an unadducted strand. The thermal destablization of the adducted 12-mers ranged from 5 to 16 °C and is dependent on the absolute stereochemistry of the adduct. The HNE adducts were also examined for their ability to form interstrand DNA-DNA cross-links when incorporated into a CpG sequence. We find that only one of the HNE stereoisomers formed interstrand DNA-DNA cross-links.