89423-49-4

Basic information

• Product Name: (R)-o-<1-((S)-1-α-naphthylethylamino)pentyl>phenol
• CAS NO: 89423-49-4
• Molecular Weight: 333.473
• Mol File: 89423-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-o-<1-((S)-1-α-naphthylethylamino)pentyl>phenol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-o-<1-((S)-1-α-naphthylethylamino)pentyl>phenol(89423-49-4)
• EPA Substance Registry System: (R)-o-<1-((S)-1-α-naphthylethylamino)pentyl>phenol(89423-49-4)

Safety Data

• Hazardous Substances Data: 89423-49-4(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 18430-91-6 1-(2-hydroxyphenyl)pentan-1-one 
• 10420-89-0 (S)-1-(1-Naphthyl)ethylamine 
• 109-72-8 n-butyllithium 
• 7073-88-3 N-salicylidene-(S)-α-maphthylamine 

Relevant articles and documents

Studies on Chiral Organo-Sulfur Compounds. I. Asymmetric Synthesis of Sulfoxides with Optically Active o-Aminoalkylphenol Derivatives

Several kinds of optically active o-aminoalkylphenols were prepared and used to develop asymmetric synthetic methods for chiral sulfoxides.The reaction of 2,3-dihydro-1,2,3-benzoxathiazine 2-oxides (derived from the o-aminoalkylphenols and thionyl chloride) with phenylmagnesium bromide, followed by treatment with alkyllithium, gave optically active sulfoxides with high enantiospecificity.Among several kinds of optically active o-aminoalkylphenols examined, the readily available aminophenol, (S)-(-)-o-phenol, was found to be the most efficient and recyclable chiral source for the asymmetric synthesis of sulfoxides.Keywords - asymmetric synthesis; chiral sulfoxide; o-aminoalkylphenol; 3,4-dihydro-1,2,3-benzoxathiazine 2-oxide; thionyl chloride