894406-80-5

Basic information

• Product Name: (3R,4S)-3-[(tert-butyl)dimethylsilyloxy]-4-[N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene
• Synonyms: (3R,4S)-3-[(tert-butyl)dimethylsilyloxy]-4-[N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene
• CAS NO: 894406-80-5
• Molecular Weight: 476.669
• Mol File: 894406-80-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3R,4S)-3-[(tert-butyl)dimethylsilyloxy]-4-[N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S)-3-[(tert-butyl)dimethylsilyloxy]-4-[N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene(894406-80-5)
• EPA Substance Registry System: (3R,4S)-3-[(tert-butyl)dimethylsilyloxy]-4-[N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene(894406-80-5)

Safety Data

• Hazardous Substances Data: 894406-80-5(Hazardous Substances Data)

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 99113-30-1 ((1S,2R)-1-benzyl-2-hydroxybut-3-enyl)carbamic acid tert-butyl ester 
• 132273-11-1 (4S,3R)-4-amino-5-phenyl-pent-1-en-3-ol 

Downstream Products

• 878441-14-6 (5R,6S)-6-benzyl-5,6-dihydro-5-diphenylphosphoryloxy-1-methylpyridin-2-one 
• 894406-88-3 (5R,6S)-6-benzyl-5,6-dihydro-5-hydroxy-1-methylpyridin-2-one 
• 896506-21-1 (5R,6S)-5-acetoxy-6-benzyl-5,6-dihydro-1-methylpyridin-2-one 
• 894406-82-7 (3R,4S)-4-(N-acryloyl-N-methylamino)-3-[(tert-butyl)dimethylsiloxy]-5-phenylpent-1-ene 
• 894406-87-2 (3R,4S)-4-(N-acryloyl-N-methylamino)-5-phenylpent-1-en-3-ol 
• 894406-81-6 (3R,4S)-3-[(tert-butyl)dimethylsiloxy]-4-[N-methyl-N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene 

Relevant articles and documents

Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-SN2′ reactions

Regio- and stereoselective anti-SN2′ alkylation of γ-phosphoryloxy-α,β-unsaturated-δ-lactams with organocopper reagents allowing the preparation of N-alkylated-α,δ- substituted-β,γ-unsaturated-δ-lactams as highly functionalized diketopiperazine

Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations

We have carefully examined the organocopper-mediated reduction-alkylation of γ-acetoxy or γ,γ-difluoro-α,β-unsaturated- δ-lactams for the synthesis of (Z)-alkene- or (E)-fluoroalkene-containing diketopiperazine mimetics. Reduction of acetates 2, 12, 14, a