89451-47-8

Basic information

• Product Name: 3-Pyridinecarbonitrile, 4-(4-bromophenyl)-1,2-dihydro-6-phenyl-2-thioxo-
• CAS NO: 89451-47-8
• Molecular Formula: C18H11BrN2S
• Molecular Weight: 367.269
• Mol File: 89451-47-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarbonitrile, 4-(4-bromophenyl)-1,2-dihydro-6-phenyl-2-thioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 4-(4-bromophenyl)-1,2-dihydro-6-phenyl-2-thioxo-(89451-47-8)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 4-(4-bromophenyl)-1,2-dihydro-6-phenyl-2-thioxo-(89451-47-8)

Safety Data

• Hazardous Substances Data: 89451-47-8(Hazardous Substances Data)

Upstream product

• 1774-66-9 3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 1122-91-4 4-bromo-benzaldehyde 
• 326-06-7 1-Phenyl-4,4,4-trifluorobutane-1,3-dione 
• 68029-54-9 3-(4-bromophenyl)-2-cyanoprop-2-enethioamide 
• 7357-70-2 Cyanothioacetamide 
• 129115-49-7 C₂₃H₁₈BrN₃OS 
• 22966-09-2 (2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 68029-54-9 (E)-3-(4-bromophenyl)-2-cyanoprop-2-enethioamide 
• 18413-03-1 N-(Phenacyl)pyridinium 
• 95639-02-4 3-(4-Bromo-phenyl)-2,4,4-tricyano-but-3-enethioic acid amide 
• 98-86-2 acetophenone 
• 103845-86-9 2-Bromo-2-[1-(4-bromo-phenyl)-3-oxo-3-phenyl-propyl]-malononitrile 
• 94360-07-3 2-(1-(4-bromophenyl)-3-oxo-3-phenylpropyl)malononitrile 
• 14990-66-0 1-(1-phenylvinyl)piperidine 

Downstream Products

• 94639-84-6 3-Amino-4-(4-bromo-phenyl)-6-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid 
• 1127227-32-0 ethyl 3-amino-4-(4-bromophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxylate 
• 1127227-30-8 1-[3-amino-4-(4-bromophenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]ethanone 
• 1127227-33-1 [3-amino-4-(4-bromophenyl)-6-phenylthieno[2,3-b]pyridin-2-yl](4-chlorophenyl)methanone 
• 1127227-31-9 3-amino-4-(4-bromophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide 
• 312755-04-7 C₂₇H₁₉BrN₂O₂S 
• 313531-27-0 C₂₅H₁₇BrN₂S 
• 1384529-41-2 C₂₀H₁₂BrN₃S 
• 313531-11-2 C₂₆H₁₇Br₂N₃OS 
• 94640-08-1 [4-(4-Bromo-phenyl)-3-cyano-6-phenyl-pyridin-2-ylsulfanyl]-acetic acid 

Relevant articles and documents

Reaction of 3-Amino-4,6-diarylthieno[2,3-b]pyridine-2-carboxamides with Ninhydrin

Abstract: The reaction of N-substituted amides of 3-amino-4,6-diarylthieno[2,3-b]pyridine-2-carboxylic acids with ninhydrin in the presence of catalytic amounts of sulfuric acid gave 1′-spiro[indene-2,2′-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine]-1,3,4′(3′

Synthesis, characterization, and reactions of pyridine-3-carbonitrile derivatives

2-Thioxopyridine-3-carbonitrile derivatives 6a-c reacted with several halogen containing reagents 7a-d to afford the corresponding thieno[2,3-b]pyridine derivatives 9a-l, respectively. Thieno[2,3-b]pyridines 9c, g,k used for the preparation of their corresponding carbohydrazide derivatives 10a-c which in turn, used as good synthons for the synthesis of N-phenylmethylenethieno[2,3-b]pyridine-2-carbohydrazides 13a-c, pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidinones 15a-c, 16a-c and 17 and 1,3,4-oxadiazole-2-thiols 20a-c and 21a-c via their reactions with benzaldehyde or benzylidenemalononitrile, triethylorthoformate and carbon disulfide followed by hydrazine hydrate respectively. Considering the data of IR, 1H NMR, mass spectra, and elemental analyses elucidated the chemical structures of the newly synthesized heterocyclic compounds. Copyright Taylor & Francis Group, LLC.

CYCLIZATION REACTIONS OF NITRILES. XXXVIII. THE STEREOSELECTIVE SYNTHESIS AND TRANSFORMATIONS OF 2-HYDROXY-2,4-DIARYL-3-(1-PYRIDINO)-5-CYANO-3,4-TRANS-1,2,3,4-TETRAHYDROPYRIDINE-6-THIOLATES

The reaction of arylmethylenecyanothioacetamides with N-phenacylpyridinium ylids or the three-component condensation of ylids, aromatic aldehydes, and cyanothioacetamide proceeds stereoselectively with the formation of 2-hydroxy-2,4-diaryl-3-(1-pyridino)-5-cyano-3,4-trans-1,2,3,4-tetrahydropyridine-6-thiolates, which are intermediates in the synthesis of 4,6-diaryl-3-cyanopyridine-2(1H)-thiones.The 6-thiolates obtained are found in half-chair conformation with trans-pseudoaxial arrangement of H3 and H4.