89458-21-9Relevant articles and documents
Rhodium-Catalyzed Annulation of Phenacyl Ammonium Salts with Propargylic Alcohols via a Sequential Dual C-H and a C-C Bond Activation: Modular Entry to Diverse Isochromenones
Nanubolu, Jagadeesh Babu,Reddy Singam, Maneesh Kumar,Sridhar Reddy, Maddi,Suresh, Vavilapalli,Suri Babu, Undamatla
supporting information, p. 7888 - 7893 (2021/10/25)
Given their omnipresence in natural products and pharmaceuticals, isochromenone congeners are one of the most privileged scaffolds to synthetic chemists. Disclosed herein is a dual (ortho/meta) C-H and C-C activation of phenacyl ammonium salts (acylammonium as traceless directing group) toward annulation with propargylic alcohols to accomplish rapid access for novel isochromenones by means of rhodium catalysis from readily available starting materials. This operationally simple protocol features broad substrate scope and wide functional group tolerance. Importantly, the protocol circumvents the need of any stoichiometric metal oxidants and proceeds under aerobic conditions.
Tert-butoxy rare earth/sodium impurity bimetallic complex, as well as preparation method and use thereof
-
Paragraph 0065-0066, (2017/07/13)
The invention discloses a tert-butoxy rare earth/sodium hetero-bimetallic complex as well as a preparation method and use thereof. The molecular formula of the tert-butoxy rare earth/sodium hetero-bimetallic complex is LnNa8[OC(CH3)3]10(OH), and Ln repres
Synthesis of functionalized alkynes via palladium-catalyzed Sonogashira reactions
Ibrahim, Mansur B.,Ali, Bassam El,Malik, Imran,Fettouhi, Mohammed
, p. 554 - 558 (2016/01/20)
A highly efficient protocol for the copper and phosphine free Sonogashira cross-coupling reactions of aryl iodides with terminal alkynes under aerobic conditions has been developed. Using 1 mol % of the palladium-bis(oxazoline) complex, Pd-BOX A, in the p